SCHEMBL8091812

SCHEMBL8091812

Cc1ccc(Cl)c2sc3ccccc3c(=O)c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.50
ALDH1A1 P00352 5/20 0.50
POLB P06746 3/20 0.50
HCRTR1 O43613 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
LMNA P02545 2/20 0.50
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
GAA P10253 1/20 0.49
APP P05067 4/20 0.47
MAOA P21397 2/20 0.47
CHRM2 P08172 2/20 0.47
HTR1A P08908 2/20 0.47
ADRA2A P08913 2/20 0.47
CHRM1 P11229 2/20 0.47
TBXA2R P21731 2/20 0.47
SLC6A2 P23975 2/20 0.47
APEX1 P27695 2/20 0.47
SLC6A4 P31645 2/20 0.47
ADRA1A P35348 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16383368 0.89 MAPT (0.52) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL10059336 0.86 MAPT (0.58) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL8086616 0.83 MAPT (0.52) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL8413396 0.83 MAOA (0.51) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL3205447 0.81 MAPT (0.50) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL8089980 0.81 MAPT (0.51) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL8078642 0.81 MAPT (0.57) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL23619106 0.79 MAPT (0.52) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL3160057 0.79 ALDH1A1 (0.62) MAPTALDH1A1POLBHCRTR1L3MBTL1
SCHEMBL11966910 0.78 MAPT (0.48) MAPTALDH1A1POLBHCRTR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6054501-A CURABILITY; GLOSSINESS; CAN BE BLENDED WITH INKS, PAINTS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2000-04-25 US disclosed
EP-0844255-A1 PHOTOPOLYMERIZATION INITIATOR AND ACTINIC RADIATION-CURABLE COMPOSITION COMPRISING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-05-27 EP disclosed