⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL668279 | 0.96 | — | — | |
| SCHEMBL15748418 | 0.79 | — | — | |
| SCHEMBL2405984 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL25405351 | 0.74 | — | — | |
| SCHEMBL17209126 | 0.74 | — | — | |
| SCHEMBL15254213 | 0.72 | ODC1 (0.45) | — | |
| SCHEMBL15253912 | 0.72 | ODC1 (0.45) | — | |
| SCHEMBL15254361 | 0.72 | ODC1 (0.45) | — | |
| SCHEMBL18653252 | 0.72 | — | — | |
| SCHEMBL15254591 | 0.72 | ODC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317102-A1 | INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. | 2021-10-14 | — | — | US | disclosed |
| US-10669306-B2 | Solid supports for use in solid-phase peptide synthesis, kits, and related methods | UNIVERSITY OF WASHINGTON (US) | 2020-06-02 | — | — | US | disclosed |
| CN-107698474-B | The synthetic method of prothetic group linking arm, its synthetic method and two ubiquitin | 中国科学技术大学 | 2019-10-22 | — | — | CN | disclosed |
| US-20190010186-A1 | SOLID SUPPORTS FOR USE IN SOLID-PHASE PEPTIDE SYNTHESIS, KITS, AND RELATED METHODS | UNIVERSITY OF WASHINGTON (US) | 2019-01-10 | — | — | US | disclosed |
| CN-107698474-A | Prothetic group linking arm, its synthetic method and the synthetic method of two ubiquitin | 中国科学技术大学 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017136690-A1 | SOLID SUPPORTS FOR USE IN SOLID-PHASE PEPTIDE SYNTHESIS, KITS, AND RELATED METHODS | UNIVERSITY OF WASHINGTON (US) | 2017-08-10 | — | — | WO | disclosed |
| EP-1681303-B1 | HASylated polypeptides, especially HASylated erythropoietin | FRESENIUS KABI DE GMBH (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-8475765-B2 | Hydroxyalkyl starch derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-8475765-B2 | Hydroxyalkyl starch derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| EP-2591009-A1 | NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES | Fresenius Kabi Deutschland GmbH (DE) | 2013-05-15 | — | — | EP | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-20060199788-A1 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. | 2006-09-07 | — | — | US | disclosed |
| EP-1663254-A2 | ANTI-INFLAMATORY PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-06-07 | — | — | EP | disclosed |
| CN-1780630-A | Phosphonate compounds having immunomodulatory activity | GILEAD SCIENCES INC (US) | 2006-05-31 | — | — | CN | disclosed |
| US-20060035866-A1 | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES, INC. | 2006-02-16 | — | — | US | disclosed |
| EP-1620110-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004100960-A2 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| WO-2004096236-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |
| US-6307018-B1 | TWO OLIGOPEPTIDES ARE LIGATED TO FORM A LIGATION PRODUCT HAVING AN AMINOTHIOESTER LINKAGE; IN A SECOND STEP, THE AMINOTHIOESTER LINKAGE REARRANGES TO FORM A PRODUCT HAVING AN N-SUBSTITUTED AMIDE LINKAGE | THE SCRIPPS RESEARCH INSTITUTE | 2001-10-23 | — | — | US | disclosed |
| WO-1998028434-A1 | GENERAL CHEMICAL LIGATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-07-02 | — | — | WO | disclosed |