Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205738 | 0.87 | SLC6A2 (0.65) | SLC6A2SLC6A4ACP3ALDH1A1HPGD | |
| SCHEMBL3199946 | 0.87 | SLC6A2 (0.58) | SLC6A2SLC6A4PKMSMN1; SMN2MEN1 | |
| SCHEMBL3202142 | 0.85 | SLC6A2 (0.64) | SLC6A2SLC6A4ACP3MEN1KMT2A | |
| SCHEMBL3207091 | 0.81 | SLC6A2 (0.57) | SLC6A2SLC6A4PKMALDH1A1MEN1 | |
| SCHEMBL3212706 | 0.80 | SLC6A2 (0.65) | SLC6A2SLC6A4ACP3ALDH1A1HPGD | |
| SCHEMBL3204236 | 0.79 | SLC6A2 (0.78) | SLC6A2SLC6A4 | |
| SCHEMBL13422570 | 0.79 | SLC6A2 (0.78) | SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL3209135 | 0.78 | SLC6A2 (0.76) | SLC6A2SLC6A4 | |
| SCHEMBL3191923 | 0.77 | SLC6A2 (0.64) | SLC6A2SLC6A4ACP3MEN1KMT2A | |
| SCHEMBL13422588 | 0.76 | SLC6A2 (1.00) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671238-B2 | Arylamino-arylpropanolamine derivatives and methods of their use | WYETH LLC (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080085938-A1 | Arylamino-Arylpropanolamine Derivatives and Methods of Their Use | WYETH (US) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085938-A1 | Arylamino-Arylpropanolamine Derivatives and Methods of Their Use | PNMT, PAH, SLC18A2 | SLC6A2 4/4885SLC6A4 6/4885PKM 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.