Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191686 | 0.85 | SLC6A2 (0.61) | SLC6A2SLC6A4MEN1KMT2ATP53 | |
| SCHEMBL3199946 | 0.84 | SLC6A2 (0.58) | SLC6A2SLC6A4MEN1KMT2APKM | |
| SCHEMBL3189006 | 0.82 | SLC6A2 (0.59) | SLC6A2SLC6A4TP53MAPTALDH1A1 | |
| SCHEMBL3206018 | 0.81 | SLC6A2 (0.61) | SLC6A2SLC6A4MEN1KMT2APKM | |
| SCHEMBL3201198 | 0.76 | SLC6A2 (0.57) | SLC6A2SLC6A4 | |
| SCHEMBL3201209 | 0.76 | SLC6A2 (0.57) | SLC6A2SLC6A4 | |
| SCHEMBL13422602 | 0.76 | SLC6A2 (0.76) | SLC6A2SLC6A4TP53MAPT | |
| SCHEMBL3199676 | 0.76 | SLC6A2 (0.76) | SLC6A2SLC6A4TP53MAPT | |
| Hydrochloric Acid SCHEMBL3211673 | 0.75 | SLC6A2 (0.74) | SLC6A2SLC6A4TP53MAPT | |
| SCHEMBL3212916 | 0.75 | SLC6A2 (0.46) | SLC6A2SLC6A4ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671238-B2 | Arylamino-arylpropanolamine derivatives and methods of their use | WYETH LLC (US) | 2010-03-02 | — | — | US | disclosed |
| WO-2008042362-A1 | ARYLAMINO-ARYLPROPANOLAMINE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-04-10 | — | — | WO | disclosed |
| US-20080085938-A1 | Arylamino-Arylpropanolamine Derivatives and Methods of Their Use | WYETH (US) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085938-A1 | Arylamino-Arylpropanolamine Derivatives and Methods of Their Use | PNMT, PAH, SLC18A2 | SLC6A2 4/4885SLC6A4 6/4885MEN1 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.