Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15553080 | 0.86 | KDM4E (0.75) | KDM4EPOLBMEN1KMT2AGAA | |
| SCHEMBL1001391 | 0.85 | KDM4E (0.74) | KDM4EPOLBMEN1KMT2AGAA | |
| SCHEMBL8160985 | 0.83 | KDM4E (0.71) | KDM4EPOLBMEN1KMT2AGAA | |
| SCHEMBL1004449 | 0.82 | KDM4E (0.69) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5784944 | 0.81 | KDM4E (0.68) | KDM4EPOLBMEN1KMT2AGAA | |
| SCHEMBL1001855 | 0.81 | KDM4E (0.66) | KDM4EPOLBMEN1KMT2AGAA | |
| SCHEMBL8585914 | 0.80 | KDM4E (0.66) | KDM4EPOLBMEN1KMT2AGAA | |
| SCHEMBL3576792 | 0.79 | ALDH1A1 (0.67) | KDM4EMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL25138713 | 0.78 | KMT2A (0.69) | KDM4EPOLBMEN1KMT2AGAA | |
| SCHEMBL1002692 | 0.76 | KDM4E (0.61) | KDM4EPOLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | claimed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | claimed |
| EP-1879660-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | claimed |
| WO-2007019931-A1 | AGENT FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-02-22 | — | — | WO | claimed |
| WO-2006119819-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | claimed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | disclosed |
| EP-2054012-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | Henkel AG & Co. KGaA (DE) | 2009-05-06 | — | — | EP | disclosed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | disclosed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | disclosed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | disclosed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | disclosed |
| WO-2008028861-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2008-03-13 | — | — | WO | disclosed |
| EP-1879660-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007019931-A1 | AGENT FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-02-22 | — | — | WO | disclosed |
| WO-2006119819-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | KRT18, KAT5, H1-5 | KDM4E 1661/4885POLB 2506/4885MEN1 4670/4885 |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | KDM4E 1659/4885POLB 2891/4885MEN1 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.