SCHEMBL320672

SCHEMBL320672

O=Cc1c(Cl)cncc1Cl

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
NPSR1 Q6W5P4 1/20 0.34
GRK2 P25098 4/20 0.33
GAA P10253 1/20 0.32
ERN1 O75460 1/20 0.31
ADRB2 P07550 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HTT P42858 2/20 0.31
MAPT P10636 1/20 0.31
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16856782 0.84 GAA (0.40) ALDH1A1TDP1MEN1KMT2ANPSR1
SCHEMBL6920756 0.84 MEN1 (0.38) ALDH1A1TDP1MEN1KMT2ANPSR1
SCHEMBL12478993 0.84 MEN1 (0.38) ALDH1A1TDP1MEN1KMT2ANPSR1
SCHEMBL1563913 0.84 ALDH1A1 (0.38) ALDH1A1TDP1MEN1KMT2ANPSR1
SCHEMBL16046033 0.84 ERN1 (0.39) ALDH1A1TDP1MEN1KMT2AGRK2
SCHEMBL23641389 0.84 MEN1 (0.38) ALDH1A1TDP1MEN1KMT2ANPSR1
SCHEMBL7613538 0.83 MAPT (0.40) ALDH1A1TDP1MEN1KMT2ANPSR1
SCHEMBL31526382 0.80 MEN1 (0.45) ALDH1A1TDP1MEN1KMT2AGRK2
SCHEMBL8142077 0.79 MEN1 (0.35) ALDH1A1TDP1MEN1KMT2AGRK2
SCHEMBL18995848 0.79 MEN1 (0.34) ALDH1A1TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119865979-A High-weldability circuit board surface treatment liquid and preparation method thereof 深圳市华京超导材料有限公司 2025-04-22 CN claimed
US-20260136833-A1 OPTOELECTRONIC COMPONENT WITH A PHOTOACTIVE LAYER DESIGNED AS A PLANAR HETEROJUNCTION HELIATEK GMBH (DE) 2026-05-14 US disclosed
US-20260055094-A1 FXR (NR1H4) MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-02-26 US disclosed
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP disclosed
US-12358903-B2 FXR (NR1H4) modulating compounds GILEAD SCIENCES, INC. (US) 2025-07-15 US disclosed
CN-120058674-A 4 (1H-pyrazol-3-yl) piperidinyl derivative, preparation method thereof and application thereof in preparation of MNK inhibitor 烟台新药创制山东省实验室 2025-05-30 CN disclosed
EP-4547670-A1 POLYMORPHIC COMPOUNDS AND USES THEREOF Tyra Biosciences, Inc. (US) 2025-05-07 EP disclosed
EP-4548730-A1 OPTOELECTRONIC COMPONENT WITH A PHOTOACTIVE LAYER DESIGNED AS A PLANAR HETEROJUNCTION Heliatek GmbH (DE) 2025-05-07 EP disclosed
CN-119865979-A High-weldability circuit board surface treatment liquid and preparation method thereof 深圳市华京超导材料有限公司 2025-04-22 CN disclosed
CN-119865979-A High-weldability circuit board surface treatment liquid and preparation method thereof 深圳市华京超导材料有限公司 2025-04-22 CN disclosed
EP-0882714-A1 SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME SS Pharmaceutical Co., Ltd. (JP) 1998-12-09 EP disclosed
US-5840724-A COMPOUNDS FOR TUMOR NECROSIS FACTOR OR ENZYME INHIBITORS OF PHOSPHODIESTERASES RHONE-POULENC RORER LIMITED (GB) 1998-11-24 US disclosed
WO-1998045294-A1 COMPOUNDS ASTRA PHARMACEUTICALS LTD. (GB) 1998-10-15 WO disclosed
EP-0741707-B1 SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS RHONE POULENC RORER LTD (GB) 1998-04-01 EP disclosed
US-5698711-A INHIBITORS OF TUMOR NECROSIS FACTOR, CYCLIC ADENOSINE-3*,5*-MONOPHOSPHATE PHOSPHODIESTERASE AND EOSINOPHILS RHONE-POULENC RORER LIMITED (GB) 1997-12-16 US disclosed
US-5679696-A FOR INHIBITING TUMOR NECROSIS FACTOR; ENZYME INHIBITORS RHONE-POULENC RORER LIMITED (GB) 1997-10-21 US disclosed
EP-0741707-A1 SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS RHONE-POULENC RORER LIMITED (GB) 1996-11-13 EP disclosed
WO-1995020578-A1 SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS RHONE-POULENC RORER LIMITED (GB) 1995-08-03 WO disclosed
EP-0652868-A1 INHIBITORS OF c-AMP PHOSPHODIESTERASE AND TNF RHONE-POULENC RORER LIMITED (GB) 1995-05-17 EP disclosed
WO-1994002465-A1 INHIBITORS OF c-AMP PHOSPHODIESTERASE AND TNF RHONE-POULENC RORER LIMITED (GB) 1994-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358903-B2 FXR (NR1H4) modulating compounds NR1H4, NR1H2, NR1H3 ALDH1A1 3805/4885TDP1 4671/4885MEN1 4302/4885
US-20260136833-A1 OPTOELECTRONIC COMPONENT WITH A PHOTOACTIVE LAYER DESIGNED AS A PLANAR HETEROJUNCTION HCN2, HCN3, HCN4 ALDH1A1 2078/4885TDP1 4620/4885MEN1 1422/4885
US-20260055094-A1 FXR (NR1H4) MODULATING COMPOUNDS NR1H4, NR1H2, NR1H3 ALDH1A1 2984/4885TDP1 4672/4885MEN1 3621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.