SCHEMBL320687

SCHEMBL320687

[c]1ccc(Cc2cc[c]cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.44
ALDH1A1 P00352 3/20 0.40
CYP3A4 P08684 3/20 0.40
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
MAPK1 P28482 1/20 0.35
TP53 P04637 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TASP1 Q9H6P5 1/20 0.32
KMT2A Q03164 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1176609 0.97 ALDH1A1 (0.45) CALM1ALDH1A1CYP3A4TSHRTDP1
SCHEMBL79755 0.88 CALM1 (0.67) CALM1ALDH1A1CYP3A4TSHRTP53
SCHEMBL7201081 0.86 CALM1 (0.63) CALM1ALDH1A1CYP3A4TSHRTP53
SCHEMBL27824048 0.86 CALM1 (0.63) CALM1ALDH1A1CYP3A4TSHRTP53
SCHEMBL27326360 0.86 CALM1 (0.63) CALM1ALDH1A1CYP3A4TSHRTP53
SCHEMBL542609 0.84 IDO1 (0.44) ALDH1A1KMT2A
SCHEMBL3032997 0.84 IDO1 (0.44) ALDH1A1CYP3A4TSHRTDP1ESR1
SCHEMBL2037583 0.84 ESR1 (0.70) ALDH1A1CYP3A4TDP1ESR1ESR2
SCHEMBL61635 0.84 CYP17A1 (0.48) ALDH1A1CYP3A4TSHRCYP2C9HPGD
SCHEMBL10337521 0.84 CALM1 (0.60) CALM1ALDH1A1CYP3A4TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 932 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240088-A1 FLAME RETARDANT POLYMERS AND PROCESSES FOR PRODUCING AND USING THE SAME ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2024-07-18 US claimed
CN-117621580-A Light broadband wave-absorbing PMI foam sandwich composite wave-absorbing structure 湖南兆恒材料科技有限公司 2024-03-01 CN claimed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN claimed
WO-2023043735-A1 FLAME RETARDANT POLYMERS AND PROCESSES FOR PRODUCING AND USING THE SAME ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-03-23 WO claimed
EP-3526211-B1 FLAME RETARDANTS BRUAG FIRE PROT AG (CH) 2023-02-22 EP claimed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN claimed
EP-3390483-B1 ENCAPSULATION PROCTER & GAMBLE (US) 2022-05-18 EP claimed
US-11046482-B1 Adhesive viscoelastic polymer and its use in lighting apparatus Tak Logic, LLC (US) 2021-06-29 US claimed
EP-2403888-B1 PROTEIN-CONTAINING EMULSIONS AND ADHESIVES, AND MANUFACTURE AND USE THEREOF EVERTREE (FR) 2021-05-12 EP claimed
US-10968204-B2 Flame retardants BRUAG FIRE PROTECTION AG (CH) 2021-04-06 US claimed
EP-0223958-A2 Crosslinked copolyamideimides and method for their preparation GENERAL ELECTRIC COMPANY (US) 1987-06-03 EP claimed
EP-0184592-A1 Novel acid-extended copolyamideimides and method for their preparation GENERAL ELECTRIC COMPANY (US) 1986-06-18 EP claimed
EP-0184591-A1 Novel copolyamideimides, prepolymers therefor and method for their preparation GENERAL ELECTRIC COMPANY (US) 1986-06-18 EP claimed
US-4539366-A POLYESTERURETHANE COPOLYMER AND ACRYLIC AND/OR VINYL POLYMER BLEND RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-09-03 US claimed
EP-0126928-A1 Blends of polyetherimides and block poly(esteramides) GENERAL ELECTRIC COMPANY (US) 1984-12-05 EP claimed
US-4481339-A PACKAGING, DIELECTRIC COATINGS, MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1984-11-06 US claimed
US-4448937-A IMPROVED IMPACT STRENGTH, RESISTANCE TO BRITTLENESS; MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1984-05-15 US claimed
US-4168364-A Cyanamides of organic primary amines as epoxy curing agents CIBA-GEIGY CORPORATION (US) 1979-09-18 US claimed
US-4118368-A DERIVATIVES OF 2,6-DIMETHYL-2,6-DIALKYL-4-AMINO-4-CARBOXYLATE-PIPERIDINES SANKYO COMPANY LIMITED (JP) 1978-10-03 US claimed
US-4075165-A 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL CIBA-GEIGY CORPORATION (US) 1978-02-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968204-B2 Flame retardants AFF1, AFF2, AFF4 CALM1 844/4885ALDH1A1 1287/4885CYP3A4 769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.