Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.50 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.50 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13421020 | 0.92 | KCNH3 (0.69) | KCNH3RECQLMCL1STAT6ESR1 | |
| SCHEMBL13420924 | 0.92 | KCNH3 (0.69) | KCNH3RECQLMCL1STAT6ESR1 | |
| SCHEMBL13421016 | 0.89 | KCNH3 (0.66) | KCNH3RECQLMCL1STAT6ESR1 | |
| SCHEMBL3203902 | 0.88 | RECQL (0.69) | KCNH3MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL13421047 | 0.88 | KCNH3 (0.64) | KCNH3RECQLMCL1STAT6ESR1 | |
| SCHEMBL12084439 | 0.87 | CA9 (0.55) | KCNH3MAPTKMT2ARECQLCA9 | |
| SCHEMBL19167235 | 0.87 | KCNH3 (0.63) | KCNH3RECQLMCL1STAT6ESR1 | |
| SCHEMBL13420997 | 0.87 | RECQL (0.71) | KCNH3MAPTRECQLMCL1STAT6 | |
| SCHEMBL19598922 | 0.87 | KCNH3 (0.63) | KCNH3RECQLMCL1STAT6ESR1 | |
| SCHEMBL13421133 | 0.86 | KCNH3 (0.61) | KCNH3RECQLMCL1STAT6ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190193050-A1 | ADSORBENT MATERIAL | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2019-06-27 | — | — | US | disclosed |
| EP-1687297-B1 | TRIAZINE DIMERS FOR THE TREATMENT OF AUTOIMMUNE DISEASES | PROMETIC BIOSCIENCES INC (CA) | 2014-06-18 | — | — | EP | disclosed |
| US-20100203650-A1 | BIOMOLECULE BINDING LIGANDS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-08-12 | — | — | US | disclosed |
| US-20100203650-A1 | BIOMOLECULE BINDING LIGANDS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-08-12 | — | — | US | disclosed |
| US-7683061-B2 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC BIOSCIENCES INC. (CA) | 2010-03-23 | — | — | US | disclosed |
| US-7683061-B2 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC BIOSCIENCES INC. (CA) | 2010-03-23 | — | — | US | disclosed |
| US-7683061-B2 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC BIOSCIENCES INC. (CA) | 2010-03-23 | — | — | US | disclosed |
| WO-2009007676-A2 | BIOMOLECULE BINDING LIGANDS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2009-01-15 | — | — | WO | disclosed |
| US-20070149528-A1 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC PHARMA SMT LIMITED (GB) | 2007-06-28 | — | — | US | disclosed |
| US-20070149528-A1 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC PHARMA SMT LIMITED (GB) | 2007-06-28 | — | — | US | disclosed |
| US-20070149528-A1 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC PHARMA SMT LIMITED (GB) | 2007-06-28 | — | — | US | disclosed |
| EP-0959975-B1 | NOVEL AFFINITY LIGANDS AND THEIR USE | NOVO NORDISK AS (DK) | 2004-12-29 | — | — | EP | disclosed |
| US-6689919-B1 | SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-02-10 | — | — | US | disclosed |
| CN-1089617-C | Novel attinity ligands and their use | NOVO NORDISK AS (DK) | 2002-08-28 | — | — | CN | disclosed |
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |
| EP-0959975-A1 | NOVEL AFFINITY LIGANDS AND THEIR USE | NOVO NORDISK A/S (DK) | 1999-12-01 | — | — | EP | disclosed |
| CN-1200680-A | Novel attinity ligands and their use | NOVO NORDISK AS (DK) | 1998-12-02 | — | — | CN | disclosed |
| WO-1997010887-A1 | NOVEL AFFINITY LIGANDS AND THEIR USE | NOVO NORDISK A/S (DK) | 1997-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149528-A1 | Triazine dimers for the treatment of autoimmune diseases | SSB, TLR5, ICOS | KCNH3 2097/4885MAPT 3428/4885KMT2A 1471/4885 |
| US-20100203650-A1 | BIOMOLECULE BINDING LIGANDS | C3AR1, GRB7, C1R | KCNH3 3680/4885MAPT 4416/4885KMT2A 3966/4885 |
| US-20190193050-A1 | ADSORBENT MATERIAL | EPCAM, CD44, VIM | KCNH3 2233/4885MAPT 883/4885KMT2A 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.