Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207206 | 0.89 | GLS (0.43) | CETP | |
| SCHEMBL3221198 | 0.88 | CETP (0.41) | CETPTACR1 | |
| SCHEMBL3198681 | 0.86 | CETP (0.39) | CETP | |
| SCHEMBL13491317 | 0.86 | CETP (0.39) | CETP | |
| SCHEMBL3205200 | 0.84 | SGMS2 (0.40) | CETPTACR1 | |
| SCHEMBL3209856 | 0.84 | CETP (0.38) | CETP | |
| SCHEMBL13491322 | 0.84 | CETP (0.38) | CETP | |
| SCHEMBL3217676 | 0.84 | CETP (0.40) | CETPTACR1 | |
| SCHEMBL3225149 | 0.83 | CETP (0.40) | CETP | |
| SCHEMBL3201375 | 0.83 | CETP (0.41) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041705-A1 | Organic Compounds | NOVARTIS AG | 2010-02-18 | — | — | US | disclosed |
| US-20100041705-A1 | Organic Compounds | NOVARTIS AG | 2010-02-18 | — | — | US | disclosed |
| US-20100041705-A1 | Organic Compounds | NOVARTIS AG | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041705-A1 | Organic Compounds | CETP, NPC1, LCAT | CETP 1/4885TACR1 1439/4885CRHR1 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.