Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 2/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341183 | 0.83 | DDB1 (0.55) | ELANEKMT2AMEN1GAAEPHX2 | |
| SCHEMBL1189753 | 0.83 | KMT2A (0.61) | ELANEKMT2AMEN1EPHX2DDB1 | |
| SCHEMBL12491711 | 0.80 | KMT2A (0.67) | ELANEKMT2AMEN1EPHX2DDB1 | |
| SCHEMBL16835494 | 0.80 | KMT2A (0.67) | ELANEKMT2AMEN1EPHX2DDB1 | |
| SCHEMBL23580689 | 0.80 | ELANE (0.45) | ELANEKMT2AMEN1GAAEPHX2 | |
| SCHEMBL23580081 | 0.79 | GAA (0.59) | ELANEKMT2AMEN1GAACTSG | |
| SCHEMBL27020595 | 0.76 | ELANE (0.39) | ELANEKMT2AMEN1GAAEPHX2 | |
| SCHEMBL3127344 | 0.76 | EPHX2 (0.54) | ELANEKMT2AMEN1GAAEPHX2 | |
| SCHEMBL13484401 | 0.76 | ELANE (0.56) | ELANEKMT2AMEN1GAAEPHX2 | |
| SCHEMBL10870338 | 0.75 | ELANE (0.55) | ELANEKMT2AMEN1GAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036120-A1 | NOVEL METHOD FOR SYNTHESIS OF 1,4-MORPHOLINE-2,5-DIONES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2010-02-11 | — | — | US | disclosed |
| US-20100036120-A1 | NOVEL METHOD FOR SYNTHESIS OF 1,4-MORPHOLINE-2,5-DIONES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2010-02-11 | — | — | US | disclosed |
| US-20100036120-A1 | NOVEL METHOD FOR SYNTHESIS OF 1,4-MORPHOLINE-2,5-DIONES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2010-02-11 | — | — | US | disclosed |
| WO-2007085729-A2 | NOVEL METHOD FOR SYNTHESIS OF 1,4-MORPHOLINE-2,5-DIONES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUE (S.C.R.A.S.) (FR) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036120-A1 | NOVEL METHOD FOR SYNTHESIS OF 1,4-MORPHOLINE-2,5-DIONES | CBR1, CBR3, NOX4 | ELANE 4632/4885KMT2A 1823/4885MEN1 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.