Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064935 | 0.86 | — | — | |
| Acetaldehyde SCHEMBL1401397 | 0.86 | TSHR (0.43) | — | |
| Acetaldehyde SCHEMBL225414 | 0.86 | — | — | |
| Acrolein SCHEMBL3133786 | 0.84 | TRPA1 (0.47) | ALDH1A1 | |
| Formic Acid Methyl Ester SCHEMBL27262749 | 0.83 | — | — | |
| Isobutyraldehyde SCHEMBL9790327 | 0.83 | — | — | |
| Formamide SCHEMBL3824232 | 0.83 | — | — | |
| Formic Acid SCHEMBL28261918 | 0.83 | — | — | |
| SCHEMBL11615697 | 0.80 | — | — | |
| SCHEMBL1153 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907344-A | Beta-carboline-1-propionic acid and indole derivatives, and preparation method and application thereof | 山东大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114634509-A | Full continuous flow preparation method of (-) -tetrahydroberberine alkaloid | 复旦大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113735847-B | Synthetic preparation method of berberine hydrochloride | 四川大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-114573576-A | Preparation method of diketone compound and preparation method of imidazole derivative | 陕西莱特光电材料股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113735847-A | Synthetic preparation method of berberine hydrochloride | 四川大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-112266378-B | Imidazole derivative containing indazole structure and preparation method and application thereof | 延边大学 | 2021-10-12 | — | — | CN | disclosed |
| CN-112266378-A | Imidazole derivative containing indazole structure and preparation method and application thereof | 延边大学 | 2021-01-26 | — | — | CN | disclosed |
| CN-101282950-B | Novel benzothiazolone derivatives | ASTRAZENECA AB | 2012-09-12 | — | — | CN | disclosed |
| US-20100210688-A1 | Novel Benzothiazolone Derivatives | ASTRAZENECA AB (SE) | 2010-08-19 | — | — | US | disclosed |
| US-7709511-B2 | Benzothiazolone derivatives | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| US-20040038991-A1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2004-02-26 | — | — | US | disclosed |
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |
| US-6013842-A | REACTING GLYOXAL AND GLYOXAL BISACETALS WITH AN EXCESS OF AN ALCOHOL IN THE PRESENCE OF AN ACID CATALYST UNTIL EQUILIBRIUM IS ACHIEVED | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-11 | — | — | US | disclosed |
| WO-1993014261-A1 | METHOD FOR CROSSLINKING INDIVIDUALIZED CELLULOSE FIBRES | WEYERHAEUSER COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
| US-4607126-A | Process for the preparation of glyoxal, alkylglyoxals and acetals thereof | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-08-19 | — | — | US | disclosed |
| US-4395575-A | ANTITUMOR, ANTIACNE AGENTS | HOFFMANN-LA ROCHE, INC. (US) | 1983-07-26 | — | — | US | disclosed |
| US-4335248-A | ANTITUMOR AGENTS AND IN THE TREATMENT OF ACNE | HOFFMANN-LA ROCHE INC. (US) | 1982-06-15 | — | — | US | disclosed |
| US-4299995-A | ANTITUMOR AGENTS AND TREATMENT OF SKIN DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1981-11-10 | — | — | US | disclosed |
| US-4231944-A | 9-FURYL SUBSTITUTED, 4- OR 6-FLUORO DERIVATIVES OF RETINOIC ACID, ANTITUMOR AGENTS, TREATMENT OF ACNE | HOFFMANN-LA ROCHE INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4171318-A | 9-(SUBSTITUTED PHENYL), 4 OR 6-FLUORO-RETINOIC ACID DERIVATIVES, ANTITUMOR AND ANTIACNE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1979-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038991-A1 | Imidazolyl-cyclic acetals | CBR1, LBR, CBR3 | ALDH1A1 1812/4885 |
| US-20100210688-A1 | Novel Benzothiazolone Derivatives | NR0B1, RB1, CCND1 | ALDH1A1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.