Acrolein

Acrolein

SCHEMBL3133786

C=CC=O.COC(C)OC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3207667 0.84 ALDH1A1 (0.36) ALDH1A1
Acetaldehyde SCHEMBL1401397 0.78 TSHR (0.43) TSHR
Acetaldehyde SCHEMBL225414 0.78
Acrolein SCHEMBL9817153 0.77
Formaldehyde SCHEMBL713072 0.77
Formic Acid Methyl Ester SCHEMBL27262749 0.75
SCHEMBL9718433 0.75
Formic Acid SCHEMBL28261918 0.75
Formamide SCHEMBL3824232 0.75
Isobutyraldehyde SCHEMBL9790327 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100112817-A1 METHOD FOR FORMlNG PATTERN OF SEMICONDUCTOR DEVICE HYNIX SEMICONDUCTOR INC. (KR) 2010-05-06 US claimed
JP-60089401-A None JP disclosed
US-12612472-B2 Ethylene-vinyl alcohol copolymer and resin composition, and molded product obtained using the same KURARAY CO., LTD. (JP) 2026-04-28 US disclosed
US-20240190814-A1 Novel Intermediates SYNGENTA CROP PROTECTION AG (CH) 2024-06-13 US disclosed
EP-4313936-A1 NOVEL INTERMEDIATES Syngenta Crop Protection AG (CH) 2024-02-07 EP disclosed
WO-2023153739-A1 NOVEL COMPOUND AND USES THEREOF 에스에프씨 주식회사 2023-08-17 WO disclosed
EP-3587460-B1 ETHYLENE-VINYL ALCOHOL COPOLYMER AND RESIN COMPOSITION, AND MOLDED PRODUCT OBTAINED USING THE SAME KURARAY CO (JP) 2023-04-05 EP disclosed
CN-110892568-B Modified triazine functional compounds 诺姆斯科技公司 2023-03-31 CN disclosed
WO-2022207428-A1 NOVEL INTERMEDIATES SYNGENTA CROP PROTECTION AG (CH) 2022-10-06 WO disclosed
CN-113166091-A Pladienolide compounds and uses thereof 卫材R&D管理有限公司 2021-07-23 CN disclosed
US-4643255-A CROSSLINKING POLYVINYL ALCOHOL WITH AN ALDEHYDE CITIES SERVICE OIL AND GAS CORPORATION (US) 1987-02-17 US disclosed
US-4607126-A Process for the preparation of glyoxal, alkylglyoxals and acetals thereof CHEMIE LINZ AKTIENGESELLSCHAFT (AT) 1986-08-19 US disclosed
EP-0188856-A1 Gel and process for retarding fluid flow CITIES SERVICE OIL & GAS CORPORATION (US) 1986-07-30 EP disclosed
EP-0186663-A1 GEL AND PROCESS FOR RETARDING FLUID FLOW. CITIES SERVICE OIL & GAS (US) 1986-07-09 EP disclosed
EP-0183280-A2 Siloxa-cyclic compounds UNION CARBIDE CORPORATION (US) 1986-06-04 EP disclosed
WO-1986000330-A1 GEL AND PROCESS FOR RETARDING FLUID FLOW CITIES SERVICE OIL AND GAS CORPORATION (US) 1986-01-16 WO disclosed
JP-S6089401-A CONTROLLER FOR MARINE LIFE ADHERENCE KURITA WATER IND LTD 1985-05-20 JP disclosed
US-4498540-A POLYVINYL ALCOHOL-ALDEHYDE GEL CITIES SERVICE OIL AND GAS CORPORATION (US) 1985-02-12 US disclosed
US-4424392-A HYDROFORMYLATION OF UNSATURATED SILANE, COUPLERS UNION CARBIDE CORPORATION (US) 1984-01-03 US disclosed
EP-0089690-A1 Aldehyde containing hydrolyzable silanes UNION CARBIDE CORPORATION (US) 1983-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190814-A1 Novel Intermediates CYP11B2, CYP11B1, COASY TRPA1 3196/4885ALDH1A1 759/4885TSHR 4682/4885
US-12612472-B2 Ethylene-vinyl alcohol copolymer and resin composition, and molded product obtained using the same SEM1, EEF1A1, EEF1D TRPA1 2906/4885ALDH1A1 204/4885TSHR 3851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.