SCHEMBL3207965

SCHEMBL3207965

CC1=CC(C)=C(CC(=O)c2cccc(C(C)(C)C)c2)C1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.54
CYP26A1 O43174 1/20 0.47
CYP26B1 Q9NR63 1/20 0.47
NR1H4 Q96RI1 1/20 0.41
HDAC8 Q9BY41 5/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC6 Q9UBN7 2/20 0.38
CTSL P07711 4/20 0.38
RXRA P19793 2/20 0.37
RXRB P28702 2/20 0.37
CTNNB1 P35222 1/20 0.36
WNT3A P56704 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
HDAC3 O15379 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3214198 0.81 ERCC5 (0.46)
SCHEMBL3202856 0.80 ACHE (0.55) ACHECYP26A1CYP26B1NR1H4HDAC8
SCHEMBL3201380 0.80 ALDH1A1 (0.46) HDAC8HDAC4HDAC2HDAC6HDAC3
SCHEMBL3202468 0.79 PARP1 (0.50) HDAC8HDAC4HDAC2HDAC6CTNNB1
SCHEMBL3213347 0.79 ACHE (0.54) ACHECYP26A1CYP26B1NR1H4HDAC8
SCHEMBL3191170 0.79 ACHE (0.54) ACHECYP26A1CYP26B1NR1H4HDAC8
SCHEMBL3191739 0.76 ACHE (0.54) ACHECYP26A1CYP26B1NR1H4HDAC8
SCHEMBL3214182 0.74 ACHE (0.54) ACHECYP26A1CYP26B1NR1H4HDAC8
SCHEMBL3190975 0.74 ACHE (0.54) ACHECYP26A1CYP26B1NR1H4HDAC8
SCHEMBL22701223 0.73 CYP26A1 (0.66) ACHECYP26A1CYP26B1NR1H4HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 ACHE 4371/4885CYP26A1 648/4885CYP26B1 960/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 ACHE 4371/4885CYP26A1 648/4885CYP26B1 960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.