Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12254042 | 0.91 | ZDHHC20 (0.40) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL8804421 | 0.85 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL2560026 | 0.84 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL36287 | 0.83 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL11951510 | 0.83 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL23421740 | 0.81 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| Hydrogen Sulfide SCHEMBL27807905 | 0.81 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL410928 | 0.81 | ZDHHC20 (0.48) | ZDHHC20ZDHHC2TSHRCA12CA9 | |
| SCHEMBL26637773 | 0.80 | ZDHHC20 (0.38) | ZDHHC20ZDHHC2TSHRALDH1A1 | |
| SCHEMBL9549571 | 0.80 | ZDHHC20 (0.37) | ZDHHC20ZDHHC2TSHRMAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041790-A1 | SELF-ETCHING DENTAL MATERIALS BASED ON (METH)ACRYLAMIDE PHOSPHATES | IVOCLAR VIVADENT AG (LI) | 2010-02-18 | — | — | US | disclosed |
| US-7622538-B2 | Polymerizable dental material, characterized in that it contains at least one (meth)acrylamide phosphate; adhesives, coating materials and composites for dental purposes; hydrolysis-stable | IVOCLAR VIVADENT AG (LI) | 2009-11-24 | — | — | US | disclosed |
| EP-1674066-B1 | Self-etching dental materials based on (meth)acrylamidophosphates | IVOCLAR VIVADENT AG (LI) | 2008-08-13 | — | — | EP | disclosed |
| EP-1674066-A1 | Self-etching dental materials based on (meth)acrylamidophosphates | Ivoclar Vivadent AG (LI) | 2006-06-28 | — | — | EP | disclosed |
| US-20060135719-A1 | Self-etching dental materials based on (METH) acrylamide phosphates | IVOCLAR VIVADENT AG (LI) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041790-A1 | SELF-ETCHING DENTAL MATERIALS BASED ON (METH)ACRYLAMIDE PHOSPHATES | MSR1, C1R, HRH3 | ZDHHC20 1283/4885ZDHHC2 2312/4885TSHR 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.