Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146704 | 0.91 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2TOP1LMNAL3MBTL1 | |
| SCHEMBL9243605 | 0.91 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2TOP1LMNAL3MBTL1 | |
| SCHEMBL9143341 | 0.88 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TOP1LMNACA12 | |
| SCHEMBL9144568 | 0.88 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TOP1LMNACA12 | |
| SCHEMBL806321 | 0.88 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TOP1LMNACA12 | |
| SCHEMBL9147045 | 0.87 | TOP1 (0.37) | ZDHHC20ZDHHC2TOP1LMNAL3MBTL1 | |
| SCHEMBL9549578 | 0.87 | LMNA (0.37) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL9144979 | 0.87 | LMNA (0.37) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL12254042 | 0.82 | ZDHHC20 (0.40) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL3208029 | 0.80 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRMAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185466-A | Hydrophilic and amphiphatic monomers, their polymers and gels and hydrophobic electrophoresis | KOZULIC BRANKO (CH) | 1993-02-09 | — | — | US | disclosed |