Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500143 | 0.89 | KDM4E (0.53) | MAPTKDM4EHSD17B10TP53MAPK1 | |
| SCHEMBL4047702 | 0.82 | ALDH1A1 (0.55) | MAPTKDM4EHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL5480782 | 0.82 | ATM (0.56) | KDM4EHSD17B10MAPK1ALDH1A1ALOX15 | |
| SCHEMBL10874427 | 0.82 | KMT2A (0.51) | MAPTKDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL13304014 | 0.81 | HTT (0.49) | MAPTKDM4EHSD17B10TP53MAPK1 | |
| SCHEMBL28353335 | 0.81 | KDM4E (0.47) | MAPTKDM4EHSD17B10TP53MAPK1 | |
| SCHEMBL30601583 | 0.81 | HTT (0.49) | MAPTKDM4EHSD17B10TP53MAPK1 | |
| SCHEMBL9188769 | 0.81 | MAPK1 (0.47) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL3450491 | 0.81 | ALDH1A1 (0.47) | MAPTKDM4EHSD17B10TP53MAPK1 | |
| SCHEMBL21222482 | 0.81 | KMT2A (0.51) | MAPTKDM4EMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625777-B | Preparation method of lubricating oil antiwear dispersant | 中国石油天然气股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-112625777-A | Preparation method of lubricating oil antiwear dispersant | 中国石油天然气股份有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112625777-B | Preparation method of lubricating oil antiwear dispersant | 中国石油天然气股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-112625777-A | Preparation method of lubricating oil antiwear dispersant | 中国石油天然气股份有限公司 | 2021-04-09 | — | — | CN | disclosed |
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | MAPT 3925/4885KDM4E 2628/4885HSD17B10 1826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.