Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | EPM2A | O95278 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31506768 | 1.00 | DYRK1A (0.55) | DYRK1ACDK9CYP2A6FLT3ADORA2A | |
| Hydrochloric Acid SCHEMBL10508897 | 0.98 | DYRK1A (0.53) | DYRK1ACDK9CYP2A6FLT3ADORA2A | |
| Methane SCHEMBL22289615 | 0.98 | DYRK1A (0.53) | DYRK1ACDK9CYP2A6FLT3ADORA2A | |
| Butane SCHEMBL27886823 | 0.88 | DYRK1A (0.46) | DYRK1ACDK9CYP2A6ADORA2AADORA1 | |
| SCHEMBL596878 | 0.81 | CYP3A4 (0.44) | DYRK1ACDK9CYP2A6CA2ALDH1A1 | |
| SCHEMBL30469316 | 0.80 | DYRK1A (0.64) | DYRK1ACDK9ADORA2AADORA1CA2 | |
| SCHEMBL20557314 | 0.80 | DYRK1A (0.64) | DYRK1ACDK9ADORA2AADORA1CA2 | |
| SCHEMBL28156511 | 0.79 | CYP3A4 (0.42) | DYRK1ACDK9CYP2A6CA2ALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27907131 | 0.79 | CYP2A6 (0.45) | DYRK1ACDK9CYP2A6CA2HTR1B | |
| Benzofuran SCHEMBL9494180 | 0.74 | CYP3A4 (0.42) | DYRK1ACDK9ADORA2AADORA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143085-A | ABS heat-resistant modifier, intermediate, high-temperature-resistant ABS material and preparation method | 四川轻化工大学 | 2023-12-01 | — | — | CN | claimed |
| CN-109134267-B | Synthetic method of aromatic amine compound | 北京大学 | 2020-11-17 | — | — | CN | claimed |
| US-20200035418-A1 | PASSIVATION OF DEFECTS IN PEROVSKITE MATERIALS FOR IMPROVED SOLAR CELL EFFICIENCY AND STABILITY | NUTECH VENTURES | 2020-01-30 | — | — | US | claimed |
| CN-109134267-A | A kind of synthetic method of aromatic amine compounds | 北京大学 | 2019-01-04 | — | — | CN | claimed |
| WO-2018152494-A1 | PASSIVATION OF DEFECTS IN PEROVSKITE MATERIALS FOR IMPROVED SOLAR CELL EFFICIENCY AND STABILITY | NUTECH VENTURES (US) | 2018-08-23 | — | — | WO | claimed |
| US-20130317100-A1 | PROCESS FOR THE PREPARATION OF 3-AROYL-5-AMINOBENZOFURAN DERIVATIVES | LEK PHARMACEUTICALS D.D. (SI) | 2013-11-28 | — | — | US | claimed |
| EP-2638024-A1 | PROCESS FOR THE PREPARATION OF 3-AROYL-5-AMINOBENZOFURAN DERIVATIVES | LEK Pharmaceuticals d.d. (SI) | 2013-09-18 | — | — | EP | claimed |
| EP-2552900-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | SANOFI (FR) | 2013-02-06 | — | — | EP | claimed |
| US-20130023677-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | SANOFI (FR) | 2013-01-24 | — | — | US | claimed |
| WO-2012062918-A1 | PROCESS FOR THE PREPARATION OF 3-AROYL-5-AMINOBENZOFURAN DERIVATIVES | LEK PHARMACEUTICALS D.D. (SI) | 2012-05-18 | — | — | WO | claimed |
| EP-2452938-A1 | Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives | LEK Pharmaceuticals d.d. (SI) | 2012-05-16 | — | — | EP | claimed |
| WO-2011121245-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | SANOFI-AVENTIS (FR) | 2011-10-06 | — | — | WO | claimed |
| EP-1351907-B1 | 2-BUTYL-3-(4- 3(DIBUTYLAMINO)PROPOXY BENZOYL)-5-NITRO-BENZOFURAN HYDROCHLORIDE AND PREPARATION THEREOF | SANOFI AVENTIS (FR) | 2006-11-15 | — | — | EP | claimed |
| US-6846936-B2 | 2-butyl-3-(4-[3(dibutylamino)propoxy]benzoyl)-5-nitro-benzofuran hydrochloride and preparation thereof | SANOFI-SYNTHELABO (FR) | 2005-01-25 | — | — | US | claimed |
| US-20040010032-A1 | 2-butyl-3-(4-[3(dibutylamino)propoxy]benzoyl)-5-nitro-benzofuran hydrochloride and preparation thereof | SANOFI (FR) | 2004-01-15 | — | — | US | claimed |
| EP-1351907-A1 | 2-BUTYL-3-(4- 3(DIBUTYLAMINO)PROPOXY BENZOYL)-5-NITRO-BENZOFURAN HYDROCHLORIDE AND PREPARATION THEREOF | Sanofi-Aventis (FR) | 2003-10-15 | — | — | EP | claimed |
| WO-2002048078-A1 | 2-BUTYL-3-(4-[3(DIBUTYLAMINO)PROPOXY]BENZOYL)-5-NITRO-BENZOFURAN HYDROCHLORIDE AND PREPARATION THEREOF | SANOFI-SYNTHELABO (FR) | 2002-06-20 | — | — | WO | claimed |
| EP-4716529-A2 | COMPOUNDS THAT RE-ACTIVATE MUTANT P53 | Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center (US) | 2026-04-01 | — | — | EP | disclosed |
| US-3963717-A | ANTIINFLAMMATORY, ANALGESIC | SANDOZ, INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3957860-A | SULFAMIC ACID | CIBA-GEIGY AG (CH) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023677-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | CYP2F1, F5, F12 | DYRK1A 3394/4885CDK9 2726/4885CYP2A6 259/4885 |
| US-20130317100-A1 | PROCESS FOR THE PREPARATION OF 3-AROYL-5-AMINOBENZOFURAN DERIVATIVES | CYP3A5, CYP4F3, CYP3A4 | DYRK1A 3601/4885CDK9 1641/4885CYP2A6 33/4885 |
| US-20040010032-A1 | 2-butyl-3-(4-[3(dibutylamino)propoxy]benzoyl)-5-nitro-benzofuran hydrochloride and preparation thereof | CYP2D6, DBF4, DUT | DYRK1A 1989/4885CDK9 3321/4885CYP2A6 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.