SCHEMBL3208460

SCHEMBL3208460

C#CCc1cccc(C(F)(F)F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.55
IDO1 P14902 2/20 0.53
MIF P14174 2/20 0.53
HTR2A P28223 2/20 0.51
HTR2B P41595 2/20 0.51
HTR2C P28335 1/20 0.51
MAOB P27338 4/20 0.50
ACP3 P15309 1/20 0.50
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
SIGMAR1 Q99720 1/20 0.45
ADRA2C P18825 1/20 0.45
SLC6A4 P31645 1/20 0.45
ADRA1A P35348 1/20 0.45
DRD3 P35462 1/20 0.45
OPRK1 P41145 1/20 0.45
MEN1 O00255 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10975173 0.85 FDFT1 (0.46) TAAR1IDO1MIFMAOBALDH1A1
SCHEMBL38024 0.81 TAAR1 (0.55) TAAR1IDO1MIFHTR2AHTR2B
SCHEMBL3636560 0.81 MIF (0.62) TAAR1IDO1MIFHTR2AHTR2B
SCHEMBL30096354 0.81 TAAR1 (0.55) TAAR1IDO1MIFHTR2AHTR2B
SCHEMBL1758495 0.81 TAAR1 (0.59) TAAR1IDO1MIFHTR2AHTR2B
SCHEMBL383921 0.79 TAAR1 (0.57) TAAR1IDO1MIFHTR2AHTR2B
SCHEMBL9350384 0.79 MEN1 (0.41) MAOBALDH1A1LMNAMEN1KMT2A
SCHEMBL3679527 0.78 TAAR1 (0.51) TAAR1IDO1MIFHTR2AHTR2B
SCHEMBL5541075 0.78 TAAR1 (0.51) TAAR1IDO1MIFHTR2AHTR2B
SCHEMBL2093444 0.78 TAAR1 (0.60) TAAR1IDO1MIFHTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1626043-B1 Heterocyclic thioesters MGI GP INC (US) 2007-12-12 EP claimed
US-20100069244-A1 Pyridine Compounds for Combating Pests BASF SE (DE) 2010-03-18 US disclosed
US-5633268-A FUNGICIDES, INSECTICIDES, PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-05-27 US disclosed
US-4411912-A Insecticidal isovaleric acid esters ZOECON CORPORATION (US) 1983-10-25 US disclosed
EP-0061713-A1 Cyclopropanecarboxylic acid esters, their production and insecticidal and acaricidal compositions containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-10-06 EP disclosed
US-4243819-A Substituted amino acids ZOECON CORPORATION (US) 1981-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069244-A1 Pyridine Compounds for Combating Pests CHRM1, PRDX1, CHRM2 TAAR1 52/4885IDO1 34/4885MIF 4320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.