Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541075 | 0.82 | TAAR1 (0.51) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL38024 | 0.78 | TAAR1 (0.55) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL3208460 | 0.78 | TAAR1 (0.55) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL1758495 | 0.78 | TAAR1 (0.59) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL3636560 | 0.78 | MIF (0.62) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL30096354 | 0.78 | TAAR1 (0.55) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL8700239 | 0.77 | MIF (0.53) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL2257 | 0.75 | TAAR1 (0.60) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL5103155 | 0.74 | TAAR1 (0.64) | TAAR1ACP3IDO1MIFHTR2A | |
| SCHEMBL3237564 | 0.74 | TAAR1 (0.64) | TAAR1ACP3IDO1MIFHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267988-A1 | PROCESSES FOR PREPARING INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF CINACALCET | MEDICHEM, S.A. (ES) | 2010-10-21 | — | — | US | disclosed |
| EP-2041056-A2 | PROCESSES FOR PREPARING INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF CINACALCET | Medichem, S.A. (ES) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008035212-A2 | PROCESSES FOR PREPARING INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF CINACALCET | MEDICHEM, S.A. (US) | 2008-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267988-A1 | PROCESSES FOR PREPARING INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF CINACALCET | SI, KRAS, PREP | TAAR1 4657/4885ACP3 568/4885IDO1 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.