SCHEMBL320850

SCHEMBL320850

Cc1nc(N)nc2nc[nH]c12

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.66
GDA Q9Y2T3 1/20 0.66
CDK2 P24941 11/20 0.61
DPP4 P27487 1/20 0.61
MAP3K5 Q99683 1/20 0.61
CDK1 P06493 11/20 0.56
CCNB1 P14635 11/20 0.56
CCNA2 P20248 10/20 0.56
CCNA1 P78396 10/20 0.56
MGMT P16455 4/20 0.54
PIN1 Q13526 2/20 0.53
HRH4 Q9H3N8 1/20 0.51
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028472 0.80 PDPK1 (0.44) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL29143272 0.80 PDPK1 (0.92) PDPK1GDACDK2DPP4MAP3K5
SCHEMBL29366073 0.79 PDPK1 (0.44) PDPK1GDACDK2DPP4MAP3K5
SCHEMBL20611894 0.79 PDPK1 (0.44) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL24053 0.79 PDPK1 (1.00) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL28206545 0.78 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
Ammonia Solution, Strong SCHEMBL27800067 0.78 XDH (0.44) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL8757979 0.78 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL27891733 0.78 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
SCHEMBL10580001 0.77 PDPK1 (0.61) PDPK1GDACDK2DPP4MAP3K5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
WO-2025137275-A1 NOVEL CAS NUCLEASES AND POLYNUCLEOTIDES ENCODING THE SAME MODERNATX, INC. (US) 2025-06-26 WO claimed
EP-4565692-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-06-11 EP claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
WO-2024129779-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-06-20 WO claimed
WO-2024031087-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-02-08 WO claimed
WO-2023215498-A2 COMPOSITIONS AND METHODS FOR CD28 ANTAGONISM MODERNATX, INC. (US) 2023-11-09 WO claimed
US-6620599-B1 Inoculating plants in cultures and mixtures comprising auxins and cytokinins, then incubating, extracting in solvents and filtering to obtain flavonoids COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-09-16 US claimed
US-6365757-B1 CULTURING TISSUES OF TAXUS WALLICHIANIA; ISOLATION BY PARTITIONING THE CULTURE PRODUCT RESIDUE, OBTAINED BY POLAR SOLVENT EXTRACTION; DESOLVENTIZING BETWEEN WATER AND CHLORINATED SOLVENTS; EVAPORATION; CHROMOTOGRAPHY; ADSORPTION; COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-04-02 US claimed
US-5817799-A 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-10-06 US claimed
US-5563049-A 2',3'-dideoxy purine nucleosides and process for the preparation thereof NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-10-08 US claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
JP-58059998-A None JP disclosed
JP-58057396-A None JP disclosed
JP-S5859998-A PREPARATION OF 2-FLUORO-6-METHYLPURINE NUCLEOSIDE YAMASA SHOYU CO LTD 1983-04-09 JP disclosed
JP-S5857395-A 2-AMINO-6-ALKOXYCARBONYLMETHYLPURINE NUCLEOSIDE YAMASA SHOYU CO LTD 1983-04-05 JP disclosed
JP-S5857396-A 2-HYDROXY-6-METHYLPURINE NUCLEOSIDE YAMASA SHOYU CO LTD 1983-04-05 JP disclosed