SCHEMBL3208631

SCHEMBL3208631

O=C(O)NS(=O)(=O)N1CCOCC1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.48
CA7 P43166 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TSHR P16473 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.42
POLB P06746 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15018117 0.80 GAA (0.42) TSHRLMNAPOLBL3MBTL1
SCHEMBL3209417 0.80 GAA (0.46) TSHRPOLBL3MBTL1
SCHEMBL6649340 0.79 KMT2A (0.56) TSHRSMN1; SMN2LMNAPOLB
SCHEMBL3204515 0.78 GAA (0.49) TSHRPOLBL3MBTL1
SCHEMBL27021615 0.77 MEN1 (0.45) CA12CA7CA14TSHRSMN1; SMN2
SCHEMBL5119622 0.76 POLB (0.47) TSHRSMN1; SMN2LMNAPOLBL3MBTL1
SCHEMBL25229177 0.75 KDM4E (0.42) CA12TSHRPOLBHSD17B10
SCHEMBL3207323 0.75 SMN1; SMN2 (0.40) SMN1; SMN2LMNAL3MBTL1
SCHEMBL23141239 0.73 APEX1 (0.43) LMNA
Hydrochloric Acid SCHEMBL7085128 0.73 POLB (0.39) CA12TSHRSMN1; SMN2LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592439-B1 AMINOSULFONYL CARBAMATES WARNER LAMBERT CO (US) 2003-07-30 EP claimed
US-20100041892-A1 Therapeutic agent for diabetes ABE HIDENORI 2010-02-18 US disclosed
US-20090270631-A1 Therapeutic agent for diabetes ABE HIDENORI 2009-10-29 US disclosed
US-20080194617-A1 Fused ring compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-08-14 US disclosed
US-20080009530-A1 Therapeutic Agent for Diabetes TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-01-10 US disclosed
EP-0592439-A1 AMINOSULFONYL CARBAMATES WARNER-LAMBERT COMPANY (US) 1994-04-20 EP disclosed
WO-1992008693-A1 AMINOSULFONYL CARBAMATES WARNER-LAMBERT COMPANY (US) 1992-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194617-A1 Fused ring compound SLC5A1, SLC5A2, GPR119 CA12 1162/4885CA7 166/4885CA14 913/4885
US-20090270631-A1 Therapeutic agent for diabetes FABP4, SLC5A1, SLC5A2 CA12 3251/4885CA7 1418/4885CA14 2880/4885
US-20080009530-A1 Therapeutic Agent for Diabetes FABP4, SLC5A1, SLC5A2 CA12 3135/4885CA7 1554/4885CA14 3444/4885
US-20100041892-A1 Therapeutic agent for diabetes FABP4, SLC5A1, SLC5A2 CA12 3251/4885CA7 1418/4885CA14 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.