Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 11/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.53 |
| ▸ | FYN | P06241 | 6/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852563 | 0.87 | NR4A2 (0.56) | MRGPRX4 | |
| Water SCHEMBL1854715 | 0.85 | NR4A2 (0.54) | MRGPRX4 | |
| Water SCHEMBL1854716 | 0.85 | NR4A2 (0.54) | MRGPRX4 | |
| SCHEMBL1854941 | 0.83 | BRAF (0.46) | MRGPRX4 | |
| SCHEMBL3209898 | 0.77 | GPR52 (0.55) | GPR52 | |
| SCHEMBL961978 | 0.73 | GPR52 (1.00) | GPR52MRGPRX4 | |
| SCHEMBL3514281 | 0.71 | POLB (0.76) | GPR52MRGPRX4 | |
| SCHEMBL22481028 | 0.69 | MRGPRX4 (1.00) | MRGPRX4 | |
| SCHEMBL3207056 | 0.69 | GPR52 (1.00) | GPR52MRGPRX4 | |
| SCHEMBL3217438 | 0.69 | GPR52 (1.00) | GPR52MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | GPR52 1/4885MRGPRX4 287/4885FYN 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.