Fluoride

Fluoride

SCHEMBL3208832

F.O=S(=O)(O)C(F)(F)C(F)(F)C(F)(F)S(=O)(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA2 P00918 5/20 0.35
CA1 P00915 4/20 0.35
MMP1 P03956 2/20 0.35
MMP2 P08253 2/20 0.35
MMP9 P14780 2/20 0.35
MMP8 P22894 2/20 0.35
MMP13 P45452 2/20 0.35
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
F2 P00734 2/20 0.31
PRSS1 P07477 2/20 0.31
PRSS2 P07478 2/20 0.31
PRSS3 P35030 2/20 0.31
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL715643 0.97 ALDH1A1 (0.43) ALDH1A1L3MBTL1TSHRTDP1CA2
SCHEMBL11889340 0.93 ALDH1A1 (0.41) ALDH1A1L3MBTL1TSHRTDP1CA2
SCHEMBL5014768 0.93 ALDH1A1 (0.41) ALDH1A1L3MBTL1TSHRTDP1CA2
Water SCHEMBL10964102 0.93 ALDH1A1 (0.41) ALDH1A1L3MBTL1TSHRTDP1CA2
SCHEMBL3743473 0.93 ALDH1A1 (0.41) ALDH1A1L3MBTL1TSHRTDP1CA2
Ammonia Solution, Strong SCHEMBL11889654 0.93 ALDH1A1 (0.41) ALDH1A1L3MBTL1TSHRTDP1CA2
SCHEMBL2499165 0.93 ALDH1A1 (0.41) ALDH1A1L3MBTL1TSHRTDP1CA2
SCHEMBL3751488 0.93 ALDH1A1 (0.41) ALDH1A1L3MBTL1TSHRTDP1CA2
SCHEMBL714652 0.90 ALDH1A1 (0.43) ALDH1A1L3MBTL1TSHRTDP1CA2
Fluoride SCHEMBL11078578 0.88 CA2 (0.42) ALDH1A1L3MBTL1TSHRTDP1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7674560-B2 Cross-linked sulphonated polymers and their preparation process HYDRO-QUEBEC (CA) 2010-03-09 US disclosed
US-20070010628-A1 Cross-linked Sulphonated Polymers and Their Preparation Process MICHOT CHRISTOPHE 2007-01-11 US disclosed
US-7034082-B2 Cross-linked sulphonated polymers and their preparation process HYDRO-QUEBEC (CA) 2006-04-25 US disclosed
US-20050027022-A1 Cross-linked sulphonated polymers and their preparation process MICHOT CHRISTOPHE (FR) 2005-02-03 US disclosed
US-6670424-B1 Cationic ion exchange resins, membranes, dimensional stability; crosslinks between sulfonyl groups attached to adjacent polymeric chains, including those with a perfluorinated skeleton HYDRO-QUEBEC (CA) 2003-12-30 US disclosed
US-6649703-B2 Crosslinking sulfonyl groups of sulfonated polymers at least some crosslinking bonds bear an ionic charge, by allowing reaction between two sulfonyl groups from adjacent polymer chains to form crosslinks; dimensional stability HYDRO-QUEBEC (CA) 2003-11-18 US disclosed
US-20020091201-A1 Cross-linked sulphonated polymers and their preparation process MICHOT CHRISTOPHE (FR) 2002-07-11 US disclosed
US-20020002240-A1 Cross-linked sulphonated polymers and method for preparing same MICHOT CHRISTOPHE (FR) 2002-01-03 US disclosed