Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.68 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12619155 | 1.00 | S1PR1 (0.68) | S1PR1PSMD11S1PR3MAP4K4PRKCD | |
| SCHEMBL3207522 | 1.00 | S1PR1 (0.68) | S1PR1PSMD11S1PR3MAP4K4PRKCD | |
| Hydrochloric Acid SCHEMBL3216849 | 0.99 | S1PR1 (0.67) | S1PR1PSMD11S1PR3MAP4K4PRKCD | |
| Hydrochloric Acid SCHEMBL3195216 | 0.99 | S1PR1 (0.67) | S1PR1PSMD11S1PR3MAP4K4PRKCD | |
| Asp-4058 SCHEMBL3195457 | 0.89 | S1PR1 (0.86) | S1PR1PSMD11S1PR3MAP4K4MINK1 | |
| Asp-4058 SCHEMBL1798268 | 0.89 | S1PR1 (0.86) | S1PR1PSMD11S1PR3MAP4K4MINK1 | |
| Asp-4058 SCHEMBL29646278 | 0.89 | S1PR1 (0.86) | S1PR1PSMD11S1PR3MAP4K4MINK1 | |
| Asp-4058 SCHEMBL3218310 | 0.89 | S1PR1 (0.86) | S1PR1PSMD11S1PR3MAP4K4MINK1 | |
| Asp-4058 SCHEMBL3219834 | 0.88 | S1PR1 (0.84) | S1PR1PSMD11S1PR3MAP4K4MINK1 | |
| Asp-4058 SCHEMBL22729322 | 0.88 | S1PR1 (0.84) | S1PR1PSMD11S1PR3MAP4K4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678820-B2 | Hetero compound | ASTELLAS PHARMA INC. (JP) | 2010-03-16 | — | — | US | claimed |
| US-20090076070-A1 | HETERO COMPOUND | ASTELLAS PHARMA INC. (JP) | 2009-03-19 | — | — | US | claimed |
| US-7951825-B2 | Hetero compound | ASTELLAS PHARMA INC. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-7951825-B2 | Hetero compound | ASTELLAS PHARMA INC. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20100168159-A1 | HETERO COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20100168159-A1 | HETERO COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-07-01 | — | — | US | disclosed |
| US-7678820-B2 | Hetero compound | ASTELLAS PHARMA INC. (JP) | 2010-03-16 | — | — | US | disclosed |
| US-7678820-B2 | Hetero compound | ASTELLAS PHARMA INC. (JP) | 2010-03-16 | — | — | US | disclosed |
| US-20090076070-A1 | HETERO COMPOUND | ASTELLAS PHARMA INC. (JP) | 2009-03-19 | — | — | US | disclosed |
| US-20090076070-A1 | HETERO COMPOUND | ASTELLAS PHARMA INC. (JP) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168159-A1 | HETERO COMPOUND | S1PR1, ENPP2, LPAR1 | S1PR1 1/4885PSMD11 2632/4885S1PR3 7/4885 |
| US-20090076070-A1 | HETERO COMPOUND | S1PR1, ENPP2, LPAR1 | S1PR1 1/4885PSMD11 2632/4885S1PR3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.