SCHEMBL3208997

SCHEMBL3208997

Cc1cc2c(cc1C)CCC2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.42
RAPGEF4 Q8WZA2 1/20 0.42
NPC1 O15118 5/20 0.40
RAB9A P51151 5/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
LMNA P02545 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.36
CDC25B P30305 1/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598875 0.93 NPC1 (0.46) POLBRAPGEF4NPC1RAB9AGRIN2D
SCHEMBL5987610 0.81 RAPGEF4 (0.36) POLBRAPGEF4NPC1RAB9AGRIN2D
SCHEMBL11980467 0.81 RAPGEF4 (0.36) POLBRAPGEF4NPC1RAB9AGRIN2D
SCHEMBL19931597 0.81 ALDH1A1 (0.48) POLBRAPGEF4LMNASMN1; SMN2NPSR1
SCHEMBL3822542 0.81 ALDH1A1 (0.48) POLBRAPGEF4GRIN2DGRIN3BGRIN1
SCHEMBL24516499 0.81 RAPGEF4 (0.36) POLBRAPGEF4NPC1RAB9AGRIN2D
SCHEMBL9912415 0.81 CD44 (0.42) POLBRAPGEF4NPC1RAB9AGRIN2D
SCHEMBL1795462 0.78 GRIN2D (0.48) RAPGEF4NPC1RAB9AGRIN2DGRIN3B
SCHEMBL361694 0.77 MAPT (0.46) NPC1SMN1; SMN2MAPTALDH1A1KDM4E
SCHEMBL20244415 0.75 MAPT (0.34) POLBRAPGEF4GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2135671-B1 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL CO (JP) 2015-03-04 EP disclosed
CN-103657631-A Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL CO 2014-03-26 CN disclosed
CN-101632925-B Catalyst and process for producing carboxylic acid and/or carboxylic acid anhydride using the same MITSUBISHI GAS CHEMICAL CO 2014-02-26 CN disclosed
US-8357625-B2 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-22 US disclosed
US-20100036138-A1 CATALYST AND METHOD FOR PRODUCING CARBOXYLIC ACID AND/OR CARBOXYLIC ANHYDRIDE IN THE PRESENCE OF THE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-11 US disclosed
CN-101632925-A Catalyst and process for producing carboxylic acid and/or carboxylic acid anhydride using the same MITSUBISHI GAS CHEMICAL CO 2010-01-27 CN disclosed
EP-2135671-A2 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst Mitsubishi Gas Chemical Company, Inc. (JP) 2009-12-23 EP disclosed
EP-1660427-A4 SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2006-12-20 EP disclosed
EP-1660427-A1 SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2006-05-31 EP disclosed
WO-2005016862-A1 SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORPORATION (JP) 2005-02-24 WO disclosed
EP-0189662-B1 NOVEL DIPHOSPHONATES AND USE THEREOF IN PHARMACEUTICAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1989-09-06 EP disclosed