SCHEMBL32090

SCHEMBL32090

COc1cc(CCC(O)CC(=O)CCc2ccccc2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 1.00
POLB P06746 1/20 1.00
TRPV1 Q8NER1 3/20 0.84
CYP3A4 P08684 5/20 0.72
CYP2C8 P10632 4/20 0.72
CYP2C9 P11712 4/20 0.72
CYP2B6 P20813 4/20 0.72
CYP2C19 P33261 4/20 0.72
LTA4H P09960 3/20 0.72
CYP1A2 P05177 3/20 0.72
HTR1A P08908 2/20 0.71
CYP2D6 P10635 2/20 0.71
CYP2A6 P11509 2/20 0.71
CYP2E1 P05181 1/20 0.71
ALOX5 P09917 3/20 0.67
OR51E2 Q9H255 1/20 0.61
ADRB2 P07550 2/20 0.57
ATM Q13315 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28766005 1.00 GAA (1.00) GAAPOLBTRPV1CYP3A4CYP2C8
SCHEMBL29908853 1.00 GAA (1.00) GAAPOLBTRPV1CYP3A4CYP2C8
Hexahydrocurcumin SCHEMBL21187516 0.94 POLB (0.88) GAAPOLBTRPV1CYP3A4CYP2C8
Hexahydrocurcumin SCHEMBL29841863 0.94 POLB (0.88) GAAPOLBTRPV1CYP3A4CYP2C8
Hexahydrocurcumin SCHEMBL290121 0.94 POLB (0.88) GAAPOLBTRPV1CYP3A4CYP2C8
SCHEMBL10848972 0.92 POLB (0.86) GAAPOLBTRPV1CYP3A4CYP2C8
SCHEMBL10860098 0.92 POLB (0.84) GAAPOLBTRPV1CYP3A4CYP2C8
SCHEMBL23229890 0.92 POLB (0.85) GAAPOLBTRPV1CYP3A4CYP2C8
SCHEMBL22417772 0.91 GAA (0.83) GAAPOLBTRPV1CYP3A4CYP2C8
SCHEMBL25512250 0.90 POLB (0.82) GAAPOLBTRPV1CYP3A4CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114533711-B Application of diphenyl heptanone compounds in preparation of drugs for improving lipid metabolism and preparation method of compounds 海南医学院 2024-01-30 CN claimed
CN-110236997-B Composition with whitening effect and preparation method thereof 佛山市普达美生物医药科技有限公司 2022-06-21 CN claimed
CN-112898143-A 5-hydroxy-7- (4-hydroxy-3-methoxyphenyl) 1-phenyl-3-heptanone separated from galangal and application thereof 海南医学院 2021-06-04 CN claimed
CN-114533711-B Application of diphenyl heptanone compounds in preparation of drugs for improving lipid metabolism and preparation method of compounds 海南医学院 2024-01-30 CN disclosed
CN-114533711-B Application of diphenyl heptanone compounds in preparation of drugs for improving lipid metabolism and preparation method of compounds 海南医学院 2024-01-30 CN disclosed
US-11540539-B2 Reduced sodium food products GENERAL MILLS, INC. (US) 2023-01-03 US disclosed
EP-3732994-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2022-11-09 EP disclosed
CN-110236997-B Composition with whitening effect and preparation method thereof 佛山市普达美生物医药科技有限公司 2022-06-21 CN disclosed
CN-110236997-B Composition with whitening effect and preparation method thereof 佛山市普达美生物医药科技有限公司 2022-06-21 CN disclosed
CN-112898143-A 5-hydroxy-7- (4-hydroxy-3-methoxyphenyl) 1-phenyl-3-heptanone separated from galangal and application thereof 海南医学院 2021-06-04 CN disclosed
CN-112898143-A 5-hydroxy-7- (4-hydroxy-3-methoxyphenyl) 1-phenyl-3-heptanone separated from galangal and application thereof 海南医学院 2021-06-04 CN disclosed
US-20150374021-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. 2015-12-31 US disclosed
US-20150374021-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. 2015-12-31 US disclosed
US-20150342233-A1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2015-12-03 US disclosed
US-20150342233-A1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2015-12-03 US disclosed
CN-101461526-B Health product with liver-protecting and sobering-up functions and preparation method thereof CHENGDU RUNXINTANG PHARMACEUTICAL CO., LTD. (CN) 2011-12-28 CN disclosed
JP-2011001386-A ADIPONECTIN PRODUCTION ENHANCER NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY 2011-01-06 JP disclosed
CN-101461526-A Health product with liver-protecting and sobering-up functions and preparation method thereof CHENGDU RUNXINTANG PHARMACEUTI (CN) 2009-06-24 CN disclosed
JP-2006045210-A ADIPONECTIN PRODUCTION ENHANCER NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL & TECHNOLOGY 2006-02-16 JP disclosed
US-20050215635-A1 Diarylheptanoid compounds and uses thereof RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215635-A1 Diarylheptanoid compounds and uses thereof CRH, HSD11B1, CYP46A1 GAA 2467/4885POLB 4827/4885TRPV1 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.