Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.55 |
| ▸ | HTR2A | P28223 | 6/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | HTR1D | P28221 | 4/20 | 0.53 |
| ▸ | HTR2B | P41595 | 5/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3192955 | 0.85 | HTR1A (0.54) | HTR2CHTR2AHTR1ASLC6A4HTR1D | |
| SCHEMBL2992667 | 0.78 | HTR1D (0.67) | HTR2CHTR2AHTR1ASLC6A4HTR1D | |
| SCHEMBL3080644 | 0.77 | HTR2C (0.55) | HTR2CHTR2AHTR1AHTR1DHTR2B | |
| SCHEMBL23069161 | 0.76 | HTR2C (0.72) | HTR2CHTR2AHTR1ASLC6A4HTR1D | |
| SCHEMBL30797919 | 0.76 | HTR2C (0.72) | HTR2CHTR2AHTR1ASLC6A4HTR1D | |
| SCHEMBL23069118 | 0.74 | HTR2C (0.72) | HTR2CHTR2AHTR1ASLC6A4HTR1D | |
| SCHEMBL24372258 | 0.72 | HTR2C (0.69) | HTR2CHTR2AHTR1ASLC6A4HTR1D | |
| SCHEMBL30183375 | 0.72 | HTR2C (0.61) | HTR2CHTR2AHTR1ASLC6A4HTR1D | |
| Bufotenine SCHEMBL29353068 | 0.72 | HTR2C (1.00) | HTR2CHTR2AHTR1ASLC6A4HTR1D | |
| Bufotenine SCHEMBL518028 | 0.72 | HTR2C (1.00) | HTR2CHTR2AHTR1ASLC6A4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | disclosed |
| US-7776844-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2010-08-17 | — | — | US | disclosed |
| US-20090208499-A1 | N-(Phosphonoalkyl)-Amino Acids, Derivatives Thereof and Compositions and Methods of Use | YU RUEY J | 2009-08-20 | — | — | US | disclosed |
| US-7572776-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2009-08-11 | — | — | US | disclosed |
| US-20080306025-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2008-12-11 | — | — | US | disclosed |
| US-7429575-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2008-09-30 | — | — | US | disclosed |
| US-20070161543-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2007-07-12 | — | — | US | disclosed |