SCHEMBL320934

SCHEMBL320934

C=C(C)C(=O)Nc1ccc2nn(-c3ccccc3O)nc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.47
RAB9A P51151 10/20 0.47
KDM4E B2RXH2 8/20 0.47
ALDH1A1 P00352 8/20 0.47
SMN1; SMN2 Q16637 6/20 0.47
CASP3 P42574 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
KMT2A Q03164 9/20 0.45
MEN1 O00255 8/20 0.45
HPGD P15428 4/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
BAZ1A Q9NRL2 1/20 0.43
MAPT P10636 7/20 0.41
HSD17B10 Q99714 4/20 0.41
TP53 P04637 3/20 0.41
MAPK1 P28482 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453094 0.88 RAB9A (0.52) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL4449676 0.88 TDP1 (0.46) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL4453728 0.86 TDP1 (0.45) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL30887146 0.86 RAB9A (0.54) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL3376787 0.86 RAB9A (0.54) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL3380577 0.83 BAZ1A (0.39) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL29400067 0.82 RXFP1 (0.42) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL508724 0.82 RXFP1 (0.42) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL4445592 0.82 TDP1 (0.41) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2
SCHEMBL10688637 0.81 NOX1 (0.46) NPC1RAB9AKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108842932-B High-adhesion polyolefin anti-adhesion film and preparation method thereof 江苏优珀斯材料科技有限公司 2021-03-19 CN disclosed
EP-2591057-B1 WATER-BASED LIQUID COLOR CONTAINING THERMOSTABLE DISPERSION ADDITIVES FOR COLORING POLY(METH)ACRYLATES EVONIK ROEHM GMBH (DE) 2019-06-12 EP disclosed
US-20180105677-A1 COLORING PROCESS FOR POLY(METH)ACRYLATES WITH WATER-BASED LIQUID DYES, AND WATER-BASED LIQUID DYES ROEHM GMBH (DE) 2018-04-19 US disclosed
CN-102971384-B Containing the water fluid colorant painted for poly-(methyl) acrylate of thermally-stabilised dispersing additive EVONIK ROHM GMBH (DE) 2016-01-20 CN disclosed
US-20150322240-A1 COLORING PROCESS FOR POLY(METH)ACRYLATES WITH WATER-BASED LIQUID DYES, AND WATER-BASED LIQUID DYES GOLCHERT URSULA (DE) 2015-11-12 US disclosed
EP-2315801-B1 COLORING PROCESS FOR POLY(METH)ACRYLATES WITH WATER-BASED LIQUID DYES, AND WATER-BASED LIQUID DYES EVONIK ROEHM GMBH (DE) 2014-11-26 EP disclosed
CN-102105520-B Coloring process for poly(meth)acrylates with water-based liquid dyes, and water-based liquid dyes EVONIK ROEHM GMBH 2014-01-15 CN disclosed
EP-1685186-B2 MOLDING MATERIAL CONTAINING A MATTING AGENT EVONIK ROEHM GMBH (DE) 2013-11-20 EP disclosed
EP-2595803-A1 TRANSPARENT, WEATHER-RESISTANT BARRIER FILM HAVING AN IMPROVED BARRIER EFFECT AND SCRATCH RESISTANCE PROPERTIES Evonik Röhm GmbH (DE) 2013-05-29 EP disclosed
EP-2591057-A2 WATER-BASED LIQUID COLOR CONTAINING THERMOSTABLE DISPERSION ADDITIVES FOR COLORING POLY(METH)ACRYLATES Evonik Röhm GmbH (DE) 2013-05-15 EP disclosed
EP-0477726-A1 Ternary mixtures of polymers RÖHM GMBH (DE) 1992-04-01 EP disclosed
US-5063112-A IMPACT-RESISTANT METHACRYLATE PROTECTIVE LAYER FOR POLYCARBONATE, CONTAINING UV ABSORBER ROHM GMBH CHEMISCHE FABRIK (DE) 1991-11-05 US disclosed
US-5061558-A METHACRYLATE PROTECTIVE COATING CONTAINING A UV-ABSORBER FOR POLYCARBONATE ROHM GMBH CHEMISCHE FABRIK (DE) 1991-10-29 US disclosed
EP-0372213-A1 Protective methycrylate layer for polycarbonate, containing a UV absorber RÖHM GMBH (DE) 1990-06-13 EP disclosed
EP-0203487-A1 Compatible polymer mixtures RÖHM GMBH (DE) 1986-12-03 EP disclosed
US-4576870-A ACRYLIC POLYMER AS UV ABSORBER ROHM GMBH (DE) 1986-03-18 US disclosed
US-4496650-A CYAN IMAGE FORMING POLYMER COUPLER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1985-01-29 US disclosed
EP-0027284-B1 COPOLYMER LATEX AND PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING SUCH LATEX AGFA-GEVAERT N.V. (BE) 1983-09-14 EP disclosed
US-4340664-A Copolymer latex and photographic silver halide materials containing such latex AGFA-GEVAERT, N.V. (BE) 1982-07-20 US disclosed
EP-0027284-A1 Copolymer latex and photographic silver halide materials containing such latex AGFA-GEVAERT N.V. (BE) 1981-04-22 EP disclosed