Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
| ▸ | PPARD | Q03181 | 6/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.55 |
| ▸ | F7 | P08709 | 5/20 | 0.55 |
| ▸ | F3 | P13726 | 5/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | FABP4 | P15090 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL10940172 | 0.82 | PPARG (0.77) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL16859918 | 0.81 | FFAR1 (0.48) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL16859919 | 0.81 | EPHX2 (0.52) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL14552385 | 0.76 | SOAT1 (0.56) | HSD17B10CYP1A2FAAHATMALDH1A1 | |
| SCHEMBL17867079 | 0.76 | PPARG (0.96) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL5370916 | 0.76 | PPARG (0.96) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL25192850 | 0.76 | PPARG (0.96) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL30641904 | 0.76 | PPARG (0.96) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL5370911 | 0.76 | PPARG (0.96) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL24450245 | 0.76 | PPARG (0.96) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170014432-A1 | COMPOSITIONS AND METHODS FOR REDUCING CHRONIC LOW-LEVEL INFLAMMATION | SEARS BARRY D (US) | 2017-01-19 | — | — | US | claimed |
| EP-3116493-A1 | COMPOSITIONS AND METHODS FOR REDUCING CHRONIC LOW-LEVEL INFLAMMATION | Sears, Barry D. (US) | 2017-01-18 | — | — | EP | claimed |
| WO-2015138224-A1 | COMPOSITIONS AND METHODS FOR REDUCING CHRONIC LOW-LEVEL INFLAMMATION | SEARS BARRY D (US) | 2015-09-17 | — | — | WO | claimed |
| US-20150190368-A1 | Novel Inhibitors of Arachidonic Acid Formation | SEARS BARRY D (US) | 2015-07-09 | — | — | US | claimed |
| US-20140056988-A1 | Novel Inhibitors of Arachidonic Acid Formation | SEARS IP LLC | 2014-02-27 | — | — | US | claimed |
| US-20120251624-A1 | NOVEL INHIBITORS OF ARACHIDONIC ACID FORMATION | SEARS BARRY D (US) | 2012-10-04 | — | — | US | claimed |
| US-20100068292-A1 | Novel Inhibitors of Arachidonic Acid Formation | SEARS BARRY D | 2010-03-18 | — | — | US | claimed |
| US-20090012157-A1 | Sesamol Derivatives as Novel Inhibitors of Arachidonic Acid Formation | SEARS BARRY D | 2009-01-08 | — | — | US | claimed |
| WO-2007092379-A2 | SESAMOL DERIVATIVES AS NOVEL INHIBITORS OF ARACHIDONIC ACID FORMATION | SEARS BARRY D (US) | 2007-08-16 | — | — | WO | claimed |
| US-20170014432-A1 | COMPOSITIONS AND METHODS FOR REDUCING CHRONIC LOW-LEVEL INFLAMMATION | SEARS BARRY D (US) | 2017-01-19 | — | — | US | disclosed |
| EP-3116493-A1 | COMPOSITIONS AND METHODS FOR REDUCING CHRONIC LOW-LEVEL INFLAMMATION | Sears, Barry D. (US) | 2017-01-18 | — | — | EP | disclosed |
| WO-2015138224-A1 | COMPOSITIONS AND METHODS FOR REDUCING CHRONIC LOW-LEVEL INFLAMMATION | SEARS BARRY D (US) | 2015-09-17 | — | — | WO | disclosed |
| US-20150190368-A1 | Novel Inhibitors of Arachidonic Acid Formation | SEARS BARRY D (US) | 2015-07-09 | — | — | US | disclosed |
| US-8987325-B2 | Inhibitors of arachidonic acid formation | SEARS IP LLC | 2015-03-24 | — | — | US | disclosed |
| US-20140056988-A1 | Novel Inhibitors of Arachidonic Acid Formation | SEARS IP LLC | 2014-02-27 | — | — | US | disclosed |
| US-20120251624-A1 | NOVEL INHIBITORS OF ARACHIDONIC ACID FORMATION | SEARS BARRY D (US) | 2012-10-04 | — | — | US | disclosed |
| US-20100068292-A1 | Novel Inhibitors of Arachidonic Acid Formation | SEARS BARRY D | 2010-03-18 | — | — | US | disclosed |
| US-20090012157-A1 | Sesamol Derivatives as Novel Inhibitors of Arachidonic Acid Formation | SEARS BARRY D | 2009-01-08 | — | — | US | disclosed |
| WO-2007092379-A2 | SESAMOL DERIVATIVES AS NOVEL INHIBITORS OF ARACHIDONIC ACID FORMATION | SEARS BARRY D (US) | 2007-08-16 | — | — | WO | disclosed |