Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783665 | 0.81 | HDAC1 (0.72) | HDAC3HDAC1HDAC6HDAC2ALDH1A1 | |
| Oleic Acid SCHEMBL3209401 | 0.81 | PPARG (0.55) | EPHX2ALDH1A1F7F3PPARG | |
| Oleic Acid SCHEMBL16859918 | 0.80 | FFAR1 (0.48) | EPHX2ALDH1A1F7F3PPARG | |
| Potassium Ion SCHEMBL27611448 | 0.78 | HDAC1 (0.57) | HDAC3HDAC1HDAC6HDAC2ALDH1A1 | |
| SCHEMBL15272035 | 0.76 | TAAR1 (0.59) | HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL11862122 | 0.76 | TAAR1 (0.59) | HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL11696002 | 0.76 | TAAR1 (0.59) | HDAC3HDAC1HDAC6HDAC2 | |
| Palmitic Acid SCHEMBL15487118 | 0.73 | CYP3A4 (0.56) | ALDH1A1PPARGPPARDPPARAALOX15 | |
| SCHEMBL9975464 | 0.73 | ACHE (0.49) | ACHEHDAC3HDAC1HDAC6ALDH1A1 | |
| SCHEMBL11697173 | 0.73 | HDAC1 (0.71) | HDAC3HDAC1HDAC6HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160066584-A9 | COMPOSITIONS AND METHOD OF CONTROLLING PHYTOPARASITIC PEST POPULATIONS | FBSCIENCES HOLDINGS, INC (US) | 2016-03-10 | — | — | US | disclosed |
| US-20150181890-A1 | COMPOSITIONS AND METHOD OF CONTROLLING PHYTOPARASITIC PEST POPULATIONS | FBSCIENCES HOLDINGS, INC (US) | 2015-07-02 | — | — | US | disclosed |