Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525080 | 0.89 | FAAH (0.58) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| SCHEMBL14552374 | 0.82 | SOAT1 (0.50) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| Piperettine SCHEMBL29371038 | 0.82 | TRPV1 (0.63) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| Piperettine SCHEMBL15159493 | 0.82 | TRPV1 (0.63) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| SCHEMBL3963333 | 0.82 | TRPV1 (0.60) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| SCHEMBL31329216 | 0.82 | TRPV1 (0.60) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| SCHEMBL14025734 | 0.82 | TRPV1 (0.60) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| Piperettine SCHEMBL29477286 | 0.82 | TRPV1 (0.63) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| SCHEMBL3963336 | 0.82 | TRPV1 (0.60) | SOAT1HDAC6HDAC3HDAC1FAAH | |
| SCHEMBL8828210 | 0.81 | HSD17B10 (0.60) | HDAC6HDAC3HDAC1CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9386767-B2 | Derivatives of dillapiol and related monolignans and use thereof | UNIVERSITY OF OTTAWA (CA) | 2016-07-12 | — | — | US | disclosed |
| US-9386767-B2 | Derivatives of dillapiol and related monolignans and use thereof | UNIVERSITY OF OTTAWA (CA) | 2016-07-12 | — | — | US | disclosed |
| US-20130012477-A1 | DERIVATIVES OF DILLAPIOL AND RELATED MONOLIGNANS AND USE THEREOF | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF HEALTH (CA) | 2013-01-10 | — | — | US | disclosed |
| US-20130012477-A1 | DERIVATIVES OF DILLAPIOL AND RELATED MONOLIGNANS AND USE THEREOF | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF HEALTH (CA) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012477-A1 | DERIVATIVES OF DILLAPIOL AND RELATED MONOLIGNANS AND USE THEREOF | CYP3A43, CYP3A4, CYP4A22 | SOAT1 453/4885HDAC6 1099/4885HDAC3 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.