SCHEMBL320943

SCHEMBL320943

CC(C)C(NC(=O)C(N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.44
NPY1R P25929 6/20 0.44
NPY2R P49146 4/20 0.44
NPY5R Q15761 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
DPP7 Q9UHL4 1/20 0.41
EPHX2 P34913 2/20 0.41
ERAP2 Q6P179 2/20 0.41
LNPEP Q9UIQ6 1/20 0.39
OTC P00480 1/20 0.38
NOD1 Q9Y239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320944 1.00 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL29532212 1.00 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30340047 0.97 NPY4R (0.43) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL29939543 0.95 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30898573 0.94 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30716491 0.94 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30148421 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30945402 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL29799968 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30456493 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106455664-A Composition with high content of cyclic dipeptide 三得利控股株式会社 2017-02-22 CN claimed
CN-106456633-A Sugar metabolism improving agent 三得利控股株式会社 2017-02-22 CN claimed
EP-4566666-A2 COMPOSITIONS AND METHODS FOR MODULATING FACTOR IX FUNCTION The Children's Hospital Of Philadelphia (US) 2025-06-11 EP disclosed
EP-3490586-B1 COMPOSITIONS AND METHODS FOR MODULATING FACTOR IX FUNCTION CHILDRENS HOSPITAL PHILADELPHIA (US) 2025-03-26 EP disclosed
EP-4473008-A2 COMPOSITIONS AND METHODS FOR TREATING FACTOR IX DEFICIENCY The Children's Hospital Of Philadelphia (US) 2024-12-11 EP disclosed
US-20230250412-A1 Compositions and Methods for Modulating Factor IX Function THE CHILDREN'S HOSPITAL OF PHILADELPHIA 2023-08-10 US disclosed
WO-2023147574-A2 COMPOSITIONS AND METHODS FOR TREATING FACTOR IX DEFICIENCY THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2023-08-03 WO disclosed
US-11708570-B2 Compositions and methods for modulating Factor IX function THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2023-07-25 US disclosed
US-20210355473-A1 CHIMERIC CLOTTING FACTORS BIOVERATIV THERAPEUTICS INC (US) 2021-11-18 US disclosed
US-10968442-B2 Chimeric clotting factors BIOVERATIV THERAPEUTICS INC. (US) 2021-04-06 US disclosed
EP-2591099-B1 CHIMERIC CLOTTING FACTORS BIOVERATIV THERAPEUTICS INC (US) 2020-11-18 EP disclosed
US-20020192794-A1 Purification of plasmin; obtain sample of plasminogen, incubate with activator, recover plasmin GRIFOLS INC. 2002-12-19 US disclosed
EP-1232252-A1 REVERSIBLY INACTIVATED ACIDIFIED PLASMIN Bayer Corporation (US) 2002-08-21 EP disclosed
EP-1232254-A1 PROCESS FOR THE PRODUCTION OF A REVERSIBLY INACTIVE ACIDIFIED PLASMIN COMPOSITION Bayer Corporation (US) 2002-08-21 EP disclosed
WO-2001036611-A1 PROCESS FOR THE PRODUCTION OF A REVERSIBLY INACTIVE ACIDIFIED PLASMIN COMPOSITION BAYER CORPORATION (US) 2001-05-25 WO disclosed
WO-2001036608-A1 REVERSIBLY INACTIVATED ACIDIFIED PLASMIN BAYER CORPORATION (US) 2001-05-25 WO disclosed
US-5407673-A Fibrinolysis and fibrinogenolysis treatment ORION THERAPEUTIC SYSTEMS, INC. (US) 1995-04-18 US disclosed
EP-0620738-A1 FIBRINOLYSIS AND FIBRINOGENOLYSIS TREATMENT WITH PLASMIN ORION THERAPEUTIC SYSTEMS, INC. (US) 1994-10-26 EP disclosed
US-5288489-A Fibrinolysis and fibrinogenolysis treatment ORION THERAPEUTIC SYSTEMS, INC. (US) 1994-02-22 US disclosed
WO-1993007893-A1 FIBRINOLYSIS AND FIBRINOGENOLYSIS TREATMENT WITH PLASMIN ORION THERAPEUTIC SYSTEMS, INC. (US) 1993-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968442-B2 Chimeric clotting factors F13B, F11, F3 NPY4R 3649/4885NPY1R 3979/4885NPY2R 4156/4885
US-20210355473-A1 CHIMERIC CLOTTING FACTORS F13B, F11, F3 NPY4R 3649/4885NPY1R 3979/4885NPY2R 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.