SCHEMBL320944

SCHEMBL320944

CC(C)[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.44
NPY1R P25929 6/20 0.44
NPY2R P49146 4/20 0.44
NPY5R Q15761 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
DPP7 Q9UHL4 1/20 0.41
EPHX2 P34913 2/20 0.41
ERAP2 Q6P179 2/20 0.41
LNPEP Q9UIQ6 1/20 0.39
OTC P00480 1/20 0.38
NOD1 Q9Y239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320943 1.00 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL29532212 1.00 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30340047 0.97 NPY4R (0.43) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL29939543 0.95 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30898573 0.94 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30716491 0.94 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30148421 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30945402 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL29799968 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2
SCHEMBL30456493 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367115-A1 Excipients To Reduce the Viscosity of Antibody Formulations and Formulation Compositions AMGEN INC. (US) 2025-12-04 US claimed
CN-119326868-B Ginseng antler refined component and preparation method and application thereof 长春中医药大学 2025-04-11 CN claimed
US-12257343-B2 Excipients to reduce the viscosity of antibody formulations and formulation compositions AMGEN INC. (US) 2025-03-25 US claimed
CN-119326868-A Ginseng antler refined component and preparation method and application thereof 长春中医药大学 2025-01-21 CN claimed
US-20250011340-A1 BENZODIAZEPINE DERIVATIVES AND ANTIBODY CONJUGATES THEREOF IMMUNOGEN, INC. 2025-01-09 US claimed
CN-113769108-B Conjugates of cysteine engineered antibodies 伊缪诺金公司 2024-11-08 CN claimed
US-20240315296-A1 PEPTIDE COMPOUNDS FOR FLAVOR MODULATING CJ CHEILJEDANG CORPORATION (KR) 2024-09-26 US claimed
EP-4412671-A1 ANTI-THROMBOGENIC COATING Medtronic, Inc. (US) 2024-08-14 EP claimed
EP-4374850-A2 METHODS OF PREVENTING METHIONINE OXIDATION IN IMMUNOCONJUGATES ImmunoGen, Inc. (US) 2024-05-29 EP claimed
EP-4364582-A1 PEPTIDE COMPOUNDS FOR FLAVOR MODULATING CJ Cheiljedang Corporation (KR) 2024-05-08 EP claimed
US-20230233697-A1 CYTOTOXIC BENZODIAZEPINE DERIVATIVES IMMUNOGEN, INC. 2023-07-27 US claimed
WO-2023059649-A1 ANTI-THROMBOGENIC COATING MEDTRONIC, INC. (US) 2023-04-13 WO claimed
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES IMMUNOGEN, INC. (US) 2023-03-30 US claimed
WO-2023277549-A1 PEPTIDE COMPOUNDS FOR FLAVOR MODULATING 씨제이제일제당 (주) 2023-01-05 WO claimed
US-20220372152-A1 ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF IMMUNOGEN, INC. 2022-11-24 US claimed
WO-2022173981-A1 INTRAVENOUS ADMINISTRATION OF ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES PEPTILOGICS, INC. (US) 2022-08-18 WO claimed
CN-106604927-B Cytotoxic benzodiazepine derivatives 伊缪诺金公司 2022-08-09 CN claimed
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IMMUNOGEN, INC. (US) 2022-05-17 US claimed
CN-106455664-A Composition with high content of cyclic dipeptide 三得利控股株式会社 2017-02-22 CN claimed
CN-106456633-A Sugar metabolism improving agent 三得利控股株式会社 2017-02-22 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233697-A1 CYTOTOXIC BENZODIAZEPINE DERIVATIVES GABRA6, GABBR1, GABRA5 NPY4R 542/4885NPY1R 294/4885NPY2R 565/4885
US-20250367115-A1 Excipients To Reduce the Viscosity of Antibody Formulations and Formulation Compositions ARGLU1, ARG1, FCGRT NPY4R 1403/4885NPY1R 1084/4885NPY2R 1670/4885
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES GABBR2, GABRB1, GABRB2 NPY4R 1324/4885NPY1R 625/4885NPY2R 784/4885
US-12257343-B2 Excipients to reduce the viscosity of antibody formulations and formulation compositions ARGLU1, ARG1, FCGRT NPY4R 1403/4885NPY1R 1084/4885NPY2R 1670/4885
US-20250011340-A1 BENZODIAZEPINE DERIVATIVES AND ANTIBODY CONJUGATES THEREOF GABRA6, GABRA2, GABRA1 NPY4R 1186/4885NPY1R 975/4885NPY2R 1467/4885
US-20220372152-A1 ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF IL23R, CD22, IL2RA NPY4R 1743/4885NPY1R 1558/4885NPY2R 1580/4885
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IL23R, CD22, IL2RA NPY4R 1743/4885NPY1R 1558/4885NPY2R 1580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.