Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Carbamate SCHEMBL30227887 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| Benzyl Carbamate SCHEMBL10700633 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| Benzyl Carbamate SCHEMBL30227819 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| Benzyl Carbamate SCHEMBL1697 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| Guanidine SCHEMBL27358697 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| SCHEMBL3662431 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| Benzyl Carbamate SCHEMBL3640975 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| Benzyl Carbamate SCHEMBL1324825 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| Benzyl Carbamate SCHEMBL1289962 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| Benzyl Carbamate SCHEMBL6944562 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590945-A2 | SERINE PROTEASE INHIBITORS | The Medicines Company (Leipzig) GmbH (DE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004678-A2 | SERINE PROTEASE INHIBITORS | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |
| EP-2231622-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | Northern Innovations and Formulations Corp. (CA) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009076743-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-25 | — | — | WO | disclosed |
| WO-2004065305-A1 | NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE | UNIVERSITY OF DAYTON (US) | 2004-08-05 | — | — | WO | disclosed |
| EP-0655439-A2 | 5,6-Bicyclic glycoprotein IIb IIIa antagonists useful in inhibition of platelet aggregation | ELI LILLY AND COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |
| US-5397781-A | Pyrimidine derivatives | MOCHIDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0561175-A1 | Pyrimidine derivatives and pharmaceutical compostions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-22 | — | — | EP | disclosed |