Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3411372 | 0.91 | HTR6 (1.00) | HTR6CHRM1 | |
| Hydrochloric Acid SCHEMBL3209749 | 0.90 | HTR6 (0.98) | HTR6CHRM1 | |
| SCHEMBL3209681 | 0.90 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3222022 | 0.90 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3407799 | 0.90 | HTR6 (1.00) | HTR6CHRM1 | |
| Hydrochloric Acid SCHEMBL3217522 | 0.89 | HTR6 (0.98) | HTR6CHRM1 | |
| SCHEMBL3221120 | 0.88 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3200826 | 0.88 | HTR6 (0.77) | HTR6 | |
| SCHEMBL3411022 | 0.81 | HTR6 (1.00) | HTR6CHRM1 | |
| SCHEMBL3413817 | 0.81 | HTR6 (0.82) | HTR6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114878-B1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2010-12-15 | — | — | EP | claimed |
| US-20100041673-A1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-02-18 | — | — | US | claimed |
| US-8470830-B2 | 5-(heterocyclyl)alkyl-N-(arylsulfonyl)indole compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2013-06-25 | — | — | US | disclosed |
| EP-2114878-B1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2010-12-15 | — | — | EP | disclosed |
| US-20100041673-A1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041673-A1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | HTR6, HTR5A, HTR2C | HTR6 1/4885CHRM1 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.