SCHEMBL3209780

SCHEMBL3209780

CC1=C(C)C(C)C(c2ccccc2/C=N/Nc2c(F)c(F)c(F)c(F)c2F)=C1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.43
GAA P10253 10/20 0.43
LMNA P02545 6/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
KMT2A Q03164 6/20 0.42
MEN1 O00255 5/20 0.42
HTT P42858 5/20 0.42
ALDH1A1 P00352 2/20 0.42
NFKB1 P19838 2/20 0.42
NFKB2 Q00653 2/20 0.42
RELA Q04206 2/20 0.42
KDM4E B2RXH2 3/20 0.34
RAB9A P51151 5/20 0.33
NPC1 O15118 3/20 0.33
POLB P06746 1/20 0.33
GPR35 Q9HC97 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
MAPK1 P28482 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3209781 1.00 MAPT (0.43) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3214581 0.84 LMNA (0.35) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3214574 0.84 LMNA (0.35) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3201623 0.83 MAPT (0.47) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3201630 0.83 MAPT (0.47) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3202041 0.82 MAPT (0.33) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3202050 0.82 MAPT (0.33) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3201869 0.81 MAPT (0.41) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3201876 0.81 MAPT (0.41) MAPTGAALMNASMN1; SMN2KMT2A
SCHEMBL3208109 0.81 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MAPT 2641/4885GAA 4642/4885LMNA 2849/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MAPT 2641/4885GAA 4642/4885LMNA 2849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.