SCHEMBL321001

SCHEMBL321001

O=S(=O)(O)C(F)=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
AKR1C3 P42330 2/20 0.43
ALDH1A1 P00352 2/20 0.43
AKR1C1 Q04828 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
FBP1 P09467 3/20 0.39
PTGS2 P35354 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
PRMT1 Q99873 1/20 0.38
PKM P14618 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2024272 0.86 AKR1C3 (0.43) TSHRAKR1C3ALDH1A1AKR1C1FBP1
SCHEMBL4127718 0.86 AKR1C3 (0.43) TSHRAKR1C3ALDH1A1AKR1C1FBP1
SCHEMBL28055679 0.83 FBP1 (0.41) TSHRAKR1C3ALDH1A1AKR1C1SMN1; SMN2
SCHEMBL28595097 0.81 PKM (0.49) TSHRAKR1C3ALDH1A1AKR1C1SMN1; SMN2
SCHEMBL8913897 0.79 TSHR (0.45) TSHRAKR1C3ALDH1A1AKR1C1SMN1; SMN2
SCHEMBL2543854 0.79 TSHR (0.45) TSHRAKR1C3ALDH1A1AKR1C1SMN1; SMN2
SCHEMBL28082912 0.77 TSHR (0.43) TSHRAKR1C3ALDH1A1AKR1C1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL18492497 0.77 TSHR (0.43) TSHRAKR1C3ALDH1A1AKR1C1SMN1; SMN2
SCHEMBL28129180 0.77 TSHR (0.43) TSHRAKR1C3ALDH1A1AKR1C1SMN1; SMN2
SCHEMBL28129681 0.77 TSHR (0.43) TSHRAKR1C3ALDH1A1AKR1C1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2529441-B1 METHOD OF MANUFACTURING PROTON-CONDUCTING MEMBRANES UNIV RAMOT (IL) 2016-05-04 EP claimed
US-8968961-B2 Method of manufacturing proton-conducting membranes RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2015-03-03 US claimed
US-20120312696-A1 METHOD OF MANUFACTURING PROTON-CONDUCTING MEMBRANES RAMOT AT TEL-AVIV UNIVERSITY LTD. 2012-12-13 US claimed
EP-2529441-A2 METHOD OF MANUFACTURING PROTON-CONDUCTING MEMBRANES Ramot at Tel Aviv University, Ltd. (IL) 2012-12-05 EP claimed
WO-2011089521-A2 METHOD OF MANUFACTURING PROTON-CONDUCTING MEMBRANES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2011-07-28 WO claimed
EP-1249053-B1 FUEL CELL WITH PROTON CONDUCTING MEMBRANE UNIV TEL AVIV FUTURE TECH DEV (IL) 2010-06-16 EP claimed
US-20030091883-A1 Fuel cell with proton conducting membrane RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2003-05-15 US claimed
EP-1249053-A2 FUEL CELL WITH PROTON CONDUCTING MEMBRANE Tel-Aviv University Future Technology Development L.P. (IL) 2002-10-16 EP claimed
US-6447943-B1 REDUCED FUEL CROSSOVER, REDUCED SENSITIVITY TO METAL ION IMPURITIES AND ABILITY TO OPERATE AT HIGHER TEMPERATURES; SOLID ELECTROLYTE MEMBRANE CONTAINS FREE ACID MOLECULES ENTRAPPED IN THE PORES OR BONDED TO THE INORGANIC POWDER RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) 2002-09-10 US claimed
WO-2001054216-A2 FUEL CELL WITH PROTON CONDUCTING MEMBRANE RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) 2001-07-26 WO claimed
US-9882223-B2 Catalysts and electrodes for fuel cells RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2018-01-30 US disclosed
US-9627693-B2 Energy storage and generation systems RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2017-04-18 US disclosed
EP-2529441-B1 METHOD OF MANUFACTURING PROTON-CONDUCTING MEMBRANES UNIV RAMOT (IL) 2016-05-04 EP disclosed
US-9331342-B2 Electrochemical systems and methods of operating same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2016-05-03 US disclosed
US-9012104-B2 Bipolar plates and regenerative fuel cell stacks including same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2015-04-21 US disclosed
CN-1411618-A Fuel cell with proton conducting membrane UNIV RAMOT (IL) 2003-04-16 CN disclosed
US-6492047-B1 Fuel cell with proton conducting membrane RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) 2002-12-10 US disclosed
EP-1249053-A2 FUEL CELL WITH PROTON CONDUCTING MEMBRANE Tel-Aviv University Future Technology Development L.P. (IL) 2002-10-16 EP disclosed
US-6447943-B1 REDUCED FUEL CROSSOVER, REDUCED SENSITIVITY TO METAL ION IMPURITIES AND ABILITY TO OPERATE AT HIGHER TEMPERATURES; SOLID ELECTROLYTE MEMBRANE CONTAINS FREE ACID MOLECULES ENTRAPPED IN THE PORES OR BONDED TO THE INORGANIC POWDER RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) 2002-09-10 US disclosed
WO-2001054216-A2 FUEL CELL WITH PROTON CONDUCTING MEMBRANE RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) 2001-07-26 WO disclosed