Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CD44 | P16070 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459701 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL1277356 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| Hydrochloric Acid SCHEMBL28259135 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| Hydrochloric Acid SCHEMBL5177923 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| Hydrochloric Acid SCHEMBL148150 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL30899710 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL3290472 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL2131880 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL5160450 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL10730713 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12209058-B2 | Method for producing aromatic aminomethyl | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2025-01-28 | — | — | US | disclosed |
| US-20220251022-A1 | METHOD FOR PRODUCING AROMATIC AMINOMETHYL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-08-11 | — | — | US | disclosed |
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
| EP-2121626-A1 | BENZIMIDAZOLE DERIVATIVES | Pfizer Products Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075196-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | ALDH1A1 680/4885CYP3A4 633/4885TSHR 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.