Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL3210147

C=CC(N)=O.C=CC(N)=O.OCCOCCOCCOCCO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.52
ALDH1A1 P00352 6/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
FGFR4 P22455 1/20 0.52
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
HSD17B10 Q99714 1/20 0.48
MAPK1 P28482 2/20 0.48
THRB P10828 2/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
CYP3A4 P08684 2/20 0.33
APP P05067 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL619243 1.00 TSHR (0.52) TSHRALDH1A1MEN1KMT2AFGFR4
Triethylene Glycol SCHEMBL617657 1.00 TSHR (0.52) TSHRALDH1A1MEN1KMT2AFGFR4
Triethylene Glycol SCHEMBL3199640 1.00 TSHR (0.52) TSHRALDH1A1MEN1KMT2AFGFR4
Pentaethylene Glycol SCHEMBL617370 1.00 TSHR (0.52) TSHRALDH1A1MEN1KMT2AFGFR4
Di(Hydroxyethyl)Ether SCHEMBL28902597 0.98 TSHR (0.55) TSHRALDH1A1MEN1KMT2AFGFR4
Di(Hydroxyethyl)Ether SCHEMBL28546498 0.98 TSHR (0.55) TSHRALDH1A1MEN1KMT2AFGFR4
Acrylamide SCHEMBL21777535 0.90 TSHR (0.42) TSHRALDH1A1MEN1KMT2AFGFR4
Triethylene Glycol SCHEMBL20379977 0.90 ALDH1A1 (0.48) TSHRALDH1A1MEN1KMT2AFGFR4
2-Ethoxyethanol SCHEMBL29191427 0.85 ALDH1A1 (0.58) TSHRALDH1A1MEN1KMT2AFGFR4
Acrylamide SCHEMBL27956962 0.85 TSHR (0.46) TSHRALDH1A1MEN1KMT2AFGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3123542-B1 GEL ELECTROLYTES AND ELECTRODES BASF SE (DE) 2018-01-10 EP disclosed
US-9755268-B2 Gel electrolytes and electrodes SION POWER CORPORATION (US) 2017-09-05 US disclosed
EP-3123542-A1 GEL ELECTROLYTES AND ELECTRODES BASF SE (DE) 2017-02-01 EP disclosed
US-20150280277-A1 GEL ELECTROLYTES AND ELECTRODES SION POWER CORPORATION (US) 2015-10-01 US disclosed
US-7683041-B2 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-03-23 US disclosed
US-20060223776-A1 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-10-05 US disclosed
US-7056901-B2 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-06-06 US disclosed
EP-1490083-A1 MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS The Regents of the University of California (US) 2004-12-29 EP disclosed
US-20030211158-A1 Microgel particles for the delivery of bioactive materials UNITED STATES DEPARTMENT OF ENERGY 2003-11-13 US disclosed
WO-2003082316-A1 MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211158-A1 Microgel particles for the delivery of bioactive materials CTSE, CHMP4B, GAA TSHR 4770/4885ALDH1A1 2991/4885MEN1 553/4885
US-20060223776-A1 Microgel particles for the delivery of bioactive materials CTSE, CHMP4B, GAA TSHR 4770/4885ALDH1A1 2991/4885MEN1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.