Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205341 | 0.82 | KMT2A (0.39) | RXFP1CSNK2A2CSNK2BCSNK2A1DPP4 | |
| SCHEMBL2084672 | 0.80 | NR4A2 (0.43) | RXFP1CSNK2A2CSNK2BCSNK2A1KMT2A | |
| SCHEMBL2084414 | 0.72 | CRHR1 (0.40) | RXFP1CRHR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3197266 | 0.70 | CRHR1 (0.47) | CRHR1DPP4HSP90AB1KMT2ACYP3A4 | |
| SCHEMBL24611913 | 0.68 | HSP90AB1 (0.42) | HSP90AB1KMT2AHTTCYP3A4THRB | |
| SCHEMBL13459581 | 0.67 | POLB (0.36) | RXFP1CRHR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL28385050 | 0.66 | HSP90AB1 (0.46) | HSP90AB1KMT2AMAPTHTTCYP3A4 | |
| SCHEMBL9720563 | 0.64 | HSP90AB1 (0.44) | CRHR1CSNK2A2CSNK2BCSNK2A1HSP90AB1 | |
| SCHEMBL24451116 | 0.64 | HSP90AB1 (0.48) | DPP4HSP90AB1KMT2ACYP3A4MEN1 | |
| SCHEMBL1260508 | 0.63 | HSP90AB1 (0.47) | DPP4HSP90AB1KMT2ACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | HRH4, SSTR5, CNR1 | RXFP1 56/4885CRHR1 4/4885CSNK2A2 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.