Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215772 | 0.89 | MAPT (0.80) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3228715 | 0.87 | MAPT (0.80) | MAPTTHRBPOLBKMT2AALDH1A1 | |
| SCHEMBL3226493 | 0.82 | MAPT (0.69) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3215666 | 0.79 | MAPT (0.74) | MAPTTHRBPOLBKMT2AALDH1A1 | |
| SCHEMBL3262164 | 0.78 | MAPT (0.67) | MAPTTHRBPOLBKMT2AALDH1A1 | |
| SCHEMBL3220058 | 0.78 | MAPT (0.60) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3226019 | 0.76 | MAPT (1.00) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3264281 | 0.75 | MAPT (0.83) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3221557 | 0.75 | MAPT (0.79) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3216606 | 0.71 | MAPT (0.74) | MAPTTHRBPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | claimed |
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | disclosed |