Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218859 | 0.85 | MAPT (0.81) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL3211542 | 0.82 | MAPT (0.74) | MAPTTHRBPOLBALDH1A1KMT2A | |
| SCHEMBL3228715 | 0.82 | MAPT (0.80) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL3262164 | 0.79 | MAPT (0.67) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL3220058 | 0.78 | MAPT (0.60) | MAPTTHRBPOLBALDH1A1KMT2A | |
| SCHEMBL264850 | 0.77 | RORC (0.52) | MAPTTHRBLMNAALDH1A1 | |
| SCHEMBL5226630 | 0.77 | RORC (0.52) | MAPTTHRBLMNAALDH1A1 | |
| SCHEMBL2789725 | 0.77 | RORC (0.52) | MAPTTHRBLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5258121 | 0.76 | RORC (0.51) | MAPTTHRBLMNAHTT | |
| Hydrochloric Acid SCHEMBL3457382 | 0.76 | RORC (0.51) | MAPTTHRBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | claimed |
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | disclosed |