Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226493 | 0.78 | MAPT (0.69) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3211542 | 0.78 | MAPT (0.74) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3228715 | 0.75 | MAPT (0.80) | MAPTTHRBPOLBKMT2ANPC1 | |
| SCHEMBL3262032 | 0.70 | MAPT (1.00) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL3262164 | 0.70 | MAPT (0.67) | MAPTTHRBPOLBKMT2AALDH1A1 | |
| SCHEMBL265268 | 0.67 | RORC (0.47) | MAPTTHRBALDH1A1 | |
| SCHEMBL265267 | 0.67 | RORC (0.47) | MAPTTHRBALDH1A1 | |
| SCHEMBL7018874 | 0.67 | RORC (0.47) | MAPTTHRBALDH1A1 | |
| SCHEMBL3215772 | 0.65 | MAPT (0.80) | MAPTTHRBPOLBKMT2AMEN1 | |
| SCHEMBL5132529 | 0.65 | MEN1 (0.46) | MAPTTHRBPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | claimed |
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | disclosed |