SCHEMBL3211961

SCHEMBL3211961

NC(=O)c1[nH]ccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3032701 0.79
SCHEMBL562266 0.74
SCHEMBL7926845 0.74 PDPK1 (0.47)
SCHEMBL6672416 0.74
SCHEMBL30471167 0.73
SCHEMBL1858044 0.73
SCHEMBL30478958 0.73
SCHEMBL13729391 0.72 CNR2 (0.43)
SCHEMBL29980105 0.72 CA2 (0.39)
Hydrochloric Acid SCHEMBL10436896 0.71 CCNC (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116779-A1 DIALKYNE COMPOUND AND USE THEREOF 上海艾力斯医药科技股份有限公司 2023-06-29 WO disclosed
US-20100035929-A1 UNNATURAL DISPYRIN ANALOGUES, PREPARATION AND USES THEREOF VANDERBILT UNIVERSITY 2010-02-11 US disclosed
WO-2009152071-A1 UNNATURAL DISPYRIN ANALOGUES, PREPARATION AND USES THEREOF VANDERBILT UNIVERSITY (US) 2009-12-17 WO disclosed
WO-2007107319-A1 ISOLATION, STRUCTURE DETERMINATION, SYNTHESIS AND BIOACTIVITY OF DAMIPIPECOLIN AND DAMITURICIN BIOTECMARIN GMBH (DE) 2007-09-27 WO disclosed