Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 14/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 14/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 14/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 14/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.66 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.66 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539554 | 0.90 | LTA4H (0.66) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| Trifluoroacetic Acid SCHEMBL3202548 | 0.88 | HDAC4 (0.66) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL13973103 | 0.85 | HDAC6 (0.69) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL14135053 | 0.83 | HDAC6 (0.72) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL28608420 | 0.83 | HDAC6 (0.72) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL4837664 | 0.83 | HDAC6 (0.72) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| Hydrochloric Acid SCHEMBL28515049 | 0.83 | HDAC6 (0.67) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL31203555 | 0.83 | HDAC6 (0.72) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| Hydrochloric Acid SCHEMBL8750137 | 0.82 | HDAC6 (0.70) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| Hydrochloric Acid SCHEMBL827279 | 0.82 | HDAC6 (0.70) | HDAC4HDAC1HDAC7HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130261178-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | MISTRY SHAILESH (GB) | 2013-10-03 | — | — | US | disclosed |
| EP-2590937-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | The University Of Nottingham (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004549-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261178-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | NR3C2, NPR3, ADRB3 | HDAC4 1531/4885HDAC1 1010/4885HDAC7 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.