Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221048 | 0.85 | MEN1 (0.46) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL15413118 | 0.79 | KMT2A (0.54) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL7005859 | 0.74 | GRIN2D (0.41) | POLBALDH1A1 | |
| SCHEMBL16654889 | 0.74 | GRIN2D (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL987100 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL27483315 | 0.73 | SMN1; SMN2 (0.46) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL7017757 | 0.73 | KDM4E (0.60) | KMT2APOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10277624 | 0.72 | CA12 (0.50) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL9918686 | 0.71 | ALDH1A1 (0.43) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL13484125 | 0.71 | CLEC4M (0.47) | MEN1KMT2APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026075-A1 | PYRIDINE DERIVATIVES AS INHIBITORS OF HIV-I REVERSE TRANSCRIPTASE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010026075-A1 | PYRIDINE DERIVATIVES AS INHIBITORS OF HIV-I REVERSE TRANSCRIPTASE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-11 | — | — | WO | disclosed |
| US-20100056535-A1 | Inhibitors of HIV-1 reverse transcriptase | ROCHE PALO ALTO LLC | 2010-03-04 | — | — | US | disclosed |
| US-20100056535-A1 | Inhibitors of HIV-1 reverse transcriptase | ROCHE PALO ALTO LLC | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056535-A1 | Inhibitors of HIV-1 reverse transcriptase | QTRT1, NQO2, QTRT2 | MEN1 4471/4885KMT2A 600/4885POLB 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.