Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13424899 | 1.00 | MEN1 (0.53) | MEN1KMT2AALDH1A1SIGMAR1TMEM97 | |
| SCHEMBL13424943 | 0.92 | SIGMAR1 (0.49) | MEN1KMT2AALDH1A1SIGMAR1TMEM97 | |
| SCHEMBL3212764 | 0.92 | SIGMAR1 (0.49) | MEN1KMT2AALDH1A1SIGMAR1TMEM97 | |
| SCHEMBL13456000 | 0.92 | SIGMAR1 (0.53) | MEN1KMT2AALDH1A1SIGMAR1TMEM97 | |
| SCHEMBL3212933 | 0.88 | TMEM97 (0.52) | MEN1KMT2ASIGMAR1TMEM97EPHX1 | |
| SCHEMBL13424945 | 0.88 | TMEM97 (0.52) | MEN1KMT2ASIGMAR1TMEM97EPHX1 | |
| SCHEMBL3200557 | 0.84 | DRD2 (0.51) | MEN1KMT2ASIGMAR1TMEM97EPHX1 | |
| SCHEMBL13424924 | 0.84 | DRD2 (0.51) | MEN1KMT2ASIGMAR1TMEM97EPHX1 | |
| SCHEMBL3204730 | 0.82 | USP30 (0.47) | MEN1KMT2AALDH1A1USP30 | |
| SCHEMBL3219079 | 0.82 | USP30 (0.47) | MEN1KMT2AALDH1A1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100055071-A1 | Anti-Viral Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-03-04 | — | — | US | disclosed |
| EP-2097405-A2 | ANTI-VIRAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20080193411-A1 | Anti-viral Compounds | GENELABS TECHNOLOGIES, INC. | 2008-08-14 | — | — | US | disclosed |
| WO-2008070447-A2 | ANTI-VIRAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080193411-A1 | Anti-viral Compounds | ZC3HAV1, ZC3HAV1L, SARS1 | MEN1 1936/4885KMT2A 3843/4885ALDH1A1 1766/4885 |
| US-20100055071-A1 | Anti-Viral Compounds | ZC3HAV1, ZC3HAV1L, SARS1 | MEN1 1936/4885KMT2A 3843/4885ALDH1A1 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.