SCHEMBL321318

SCHEMBL321318

Cc1c[nH]c2cccc(O)c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 9/20 0.54
HTR2C P28335 7/20 0.54
HTR2B P41595 7/20 0.54
HTR1A P08908 3/20 0.51
DRD1 P21728 1/20 0.51
HTR1D P28221 1/20 0.51
HTR1B P28222 1/20 0.51
HTR1E P28566 1/20 0.51
ADORA2A P29274 1/20 0.51
ADORA2B P29275 1/20 0.51
HTR7 P34969 1/20 0.51
DRD3 P35462 1/20 0.51
HTR5A P47898 1/20 0.51
HTR6 P50406 1/20 0.51
GAA P10253 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9651757 0.80 HTR2C (0.56) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL29450053 0.80 HTR2C (0.56) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL1224614 0.80 GPR84 (0.64) HTR2AHTR2CHTR2BKDM4EMEN1
SCHEMBL30552280 0.80 GPR84 (0.64) HTR2AHTR2CHTR2BKDM4EMEN1
SCHEMBL18708141 0.77 GPR84 (0.50) HTR2AHTR2CHTR2BKDM4EMEN1
SCHEMBL12093634 0.75 GPR84 (0.58) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL398138 0.75 GPR84 (0.48) HTR2AHTR2CDRD1DRD3KDM4E
SCHEMBL3614670 0.75 CYP2A6 (0.55) HTR2AKDM4EMEN1ALDH1A1MAPT
SCHEMBL9333774 0.75 MAOA (0.38) HTR2AHTR2CHTR2BHTR1ADRD1
SCHEMBL13969931 0.75 GPR84 (0.48) HTR2AHTR2CHTR2BHTR1ADRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114324723-A Qualitative detection method for radish glucosinolates 湖北省农业科学院经济作物研究所 2022-04-12 CN claimed
CN-113391001-A Detection method of glucosinolate compounds 上海市农业科学院 2021-09-14 CN claimed
CN-111624270-A Extraction and detection method of rapeseed glucosinolate 中国农业科学院油料作物研究所 2020-09-04 CN claimed
CN-111601896-A Brassicaceae products containing isothiocyanates and methods of making the same 联邦科学技术研究组织 2020-08-28 CN claimed
US-20200255872-A1 Isothiocyanate containing Brassicaceae Products and Method of Preparation Thereof COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2020-08-13 US claimed
EP-3688179-A1 ISOTHIOCYANATE CONTAINING BRASSICACEAE Commonwealth Scientific and Industrial Research Organisation (AU) 2020-08-05 EP claimed
CN-111297931-A Broccoli total effective part extract and preparation method and application thereof 成都市三禾田生物技术有限公司 2020-06-19 CN claimed
WO-2019060963-A1 ISOTHIOCYANATE CONTAINING BRASSICACEAE PRODUCTS AND METHOD OF PREPARATION THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2019-04-04 WO claimed
US-20160331725-A1 USE OF COMPOUNDS THAT ARE ABLE TO INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASE STATES ASSOCIATED WITH A REDUCED IGF-1 SERUM LEVEL IN HUMANS AND ANIMALS VEIJLEN N.V. 2016-11-17 US claimed
JP-4641942-B2 2011-03-02 JP claimed
EP-1569628-A1 NOVEL USE OF LYCOPENE DSM IP Assets B.V. (NL) 2005-09-07 EP claimed
WO-2005039546-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES VEIJLEN N.V. (AN) 2005-05-06 WO claimed
EP-1476143-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP Assets B.V. (NL) 2004-11-17 EP claimed
WO-2004052351-A1 NOVEL USE OF LYCOPENE DSM IP ASSETS B.V. (CH) 2004-06-24 WO claimed
WO-2003068202-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP ASSETS B.V. (NL) 2003-08-21 WO claimed
US-6225533-B1 SEEDS FROM GENETIC ENGINEERING WITH MAXIMUM; ANIMAL FEEDS CARGILL, INCORPORATED 2001-05-01 US claimed
EP-0685993-B1 LOW LEVEL GLUCOSINOLATE $i(BRASSICA) CARGILL INC (US) 2000-04-26 EP claimed
US-5866762-A Low level glucosinolate brassica CARGILL INCORPORATED (US) 1999-02-02 US claimed
EP-0685993-A1 LOW LEVEL GLUCOSINOLATE $i(BRASSICA) CARGILL, INCORPORATED (US) 1995-12-13 EP claimed
WO-1994019929-A2 LOW LEVEL GLUCOSINOLATE $i(BRASSICA) CARGILL, INCORPORATED (US) 1994-09-15 WO claimed