Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327810 | 0.93 | ALDH1A1 (0.35) | TSHRHSD17B10TYRMEN1MAPT | |
| SCHEMBL16959951 | 0.86 | AR (0.34) | MEN1KMT2A | |
| SCHEMBL4868376 | 0.80 | LIPG (0.43) | TSHRHSD17B10LIPGTYRTP53 | |
| SCHEMBL829393 | 0.80 | LIPG (0.43) | TSHRHSD17B10LIPGTYRTP53 | |
| SCHEMBL828966 | 0.80 | LIPG (0.43) | TSHRHSD17B10LIPGTYRTP53 | |
| SCHEMBL1334347 | 0.80 | LIPG (0.43) | TSHRHSD17B10LIPGTYRTP53 | |
| SCHEMBL4865770 | 0.80 | LIPG (0.43) | TSHRHSD17B10LIPGTYRTP53 | |
| SCHEMBL1335248 | 0.80 | LIPG (0.43) | TSHRHSD17B10LIPGTYRTP53 | |
| SCHEMBL4863392 | 0.80 | LIPG (0.43) | TSHRHSD17B10LIPGTYRTP53 | |
| SCHEMBL677099 | 0.78 | LIPG (0.40) | TSHRHSD17B10LIPGTYRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |