Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16153732 | 0.84 | CYP1A2 (0.45) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL12305659 | 0.83 | CYP1A2 (0.53) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL13219272 | 0.78 | HSP90AA1 (0.44) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL13888086 | 0.77 | HSD17B10 (0.56) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL3089365 | 0.77 | ALDH1A1 (0.45) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL11505512 | 0.76 | HSD17B10 (0.62) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL67608 | 0.76 | HSP90AA1 (0.74) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL11591649 | 0.76 | CHEK1 (0.56) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL14871014 | 0.74 | EGFR (0.41) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL29577605 | 0.74 | HSD17B10 (0.59) | HSD17B10ALDH1A1CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102424654-A | In-situ synthesis method of 2, 4-dichloro-6-dimethylaminomethylphenol | UNIV GUILIN TECH GUT | 2012-04-25 | — | — | CN | disclosed |
| CN-102424654-A | In-situ synthesis method of 2, 4-dichloro-6-dimethylaminomethylphenol | UNIV GUILIN TECH GUT | 2012-04-25 | — | — | CN | disclosed |
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2088861-A2 | BENZIMIDAZOLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008051533-A2 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |
| EP-0153476-B1 | PROCESS FOR THE PREPARATION OF HYDROXYPHENYLACETIC-ACID AMIDES | BASF Aktiengesellschaft (DE) | 1986-10-15 | — | — | EP | disclosed |
| EP-0153476-A1 | Process for the preparation of hydroxyphenylacetic-acid amides | BASF Aktiengesellschaft (DE) | 1985-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | HRH4, SSTR5, CNR1 | HSD17B10 1266/4885ALDH1A1 1562/4885CYP2C9 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.